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The purpose of this study is to understand real world gefitinib usage patterns, patient characteristics and outcomes and to present these for a Caucasian population
A multicentre, retrospective chart review study to characterise gefitinib usage and outcomes in routine treatment
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Gefitinib |
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| Measure | Description | Time Frame |
|---|---|---|
| Assessment of treatment duration, as a surrogate of Clinical Benefit (CB) in a 'Real World' population treated with gefitinib | Retrospective population [2009 to 2013] | 6 months |
| Assessment of Overall Survival (OS) in a 'Real World' population treated with gefitinib | Retrospective population [2009 to 2013] | 6 months |
| Measure | Description | Time Frame |
|---|---|---|
| Assessment of Overall Survival (OS) in the subgroup of patients of Caucasian ethnicity and in the subgroup of patients treated with gefitinib for at least 3 months | Retrospective population [2009 to 2013] | 6 months |
| Assessment of Treatment duration in the subgroup of patients of Caucasian ethnicity and in the subgroup of patients treated with gefitinib for at least 3 months |
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Inclusion Criteria:
Exclusion Criteria:
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hospital clinic
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| Name | Affiliation | Role |
|---|---|---|
| Fiona Blackhall, MBCHB FRCP | The Christie NHS Foundation Trust | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Queen Elizabeth Hospital | Birmingham | United Kingdom | ||||
| Velindre Nhs Trust |
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| ID | Term |
|---|---|
| D008175 | Lung Neoplasms |
| ID | Term |
|---|---|
| D012142 | Respiratory Tract Neoplasms |
| D013899 | Thoracic Neoplasms |
| D009371 | Neoplasms by Site |
| D009369 | Neoplasms |
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Retrospective population [2009 to 2013] |
| 6 months |
| Characteristics of patients treated with gefitinib for all patients and stratified by whether gefitinib discontinued treatment before or after three months | Retrospective population [2009 to 2013] | 6 months |
| Description of treatment patterns in patients treated with gefitinib (prior chemo, treatment breaks, treatment on discontinuation) | Retrospective population [2009 to 2013] | 6 months |
| Duration of treatment in patients stratified by age, gender, stage and performance status. | Retrospective population [2009 to 2013] | 6 months |
| Overall Survival (OS) in patients stratified by age, gender, stage and performance status. | Retrospective population [2009 to 2013] | 6 months |
| Cardiff |
| United Kingdom |
| Harrogate District Hospital | Harrogate | United Kingdom |
| Leeds Teaching Hospitals | Leeds | United Kingdom |
| Liverpool Heart and Chest Hospital | Liverpool | United Kingdom |
| Mount Vernon Hospital Nhs Trust | London | United Kingdom |
| Royal Marsden Hospital | London | United Kingdom |
| University College Hospital | London | United Kingdom |
| Christie Hospital Nhs Trust | Manchester | United Kingdom |
| Nottingham University Hospitals Nhs Trust | Nottingham | United Kingdom |
| Northern General Hospital | Sheffield | United Kingdom |
| York District Hospital | York | United Kingdom |
| D008171 |
| Lung Diseases |
| D012140 | Respiratory Tract Diseases |