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Objective:
Due to high mortality rates the capillary leakage and the acute abdomen are important risk factors of the probability of survival. The aim of an optimal therapy of the acute abdomen within the neonatal period is beside the cure of the underlying disease the prophylaxis of capillary leakage with the help of optimised intra- and postoperative volume therapy.
Question:
Do the neonates with very low birth weight and a surgery therapy of acute abdomen benefit from early increase of the haemoglobin/haematocrit by optimised volume therapy with crystalloid and colloidal volume as prophylaxis of the capillary leakage?
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Neonates | Neonates with very low birth weight and surgery therapy of acute abdomen |
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| Measure | Description | Time Frame |
|---|---|---|
| Postoperative Capillary Leakage | Postoperative Capillary Leakage (defined as weight gain within 48 hours or development of oedema within 48 hours) | 48 hours from Baseline (Operation) |
| Measure | Description | Time Frame |
|---|---|---|
| Amount of transfusions during surgery | Up to 5 hours | |
| Re-surgery rate | Participants will be followed for the duration of hospital stay, an expected average of 12 weeks | |
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Inclusion criteria:
Exclusion criteria:
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Neonates with very low birth weight and surgery therapy of acute abdomen
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Department of Anesthesiology and Intensive Care Medicine, CCM and CVK, Charité - University Berlin | Berlin | State of Berlin | 13353 | Germany |
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| ID | Term |
|---|---|
| D000006 | Abdomen, Acute |
| ID | Term |
|---|---|
| D015746 | Abdominal Pain |
| D010146 | Pain |
| D009461 | Neurologic Manifestations |
| D012816 | Signs and Symptoms |
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| Length of stay |
| Participants will be followed for the duration of hospital stay, an expected average of 12 weeks |
| Mortality | Up to 1 year |
| D013568 |
| Pathological Conditions, Signs and Symptoms |
| D012817 | Signs and Symptoms, Digestive |