A French Non Interventional Multicentric Cohort Study in Patients With Colorectal Dysplasia

A French Non Interventional Multicentric Cohort Study in Patients With Colorectal Dysplasia in Intestinal Inflammatory Diseases

The main purpose is to describe clinical practices nowadays prospectively about patients with a dysplasia diagnosis or another histological lesions.

It will be identified colic situation during the initial colonoscopy after dysplasia diagnosis or atypical lesion.

Also the frequency and the type of monitoring conducted about these patients(surgical and endoscopic treatments).

The main criterion evaluation will be the surgical and endoscopic rates during the time.

The treatments offered such as surgical, endoscopic ones or none of them will be followed.

Finally, the outcome of these patients: stability, lesion disappearance, surgery or development of cancer with frequencies for each of them and relationships with histological abnormal colorectal lesion will be measured.

A replay centralized pathological lesion slides corresponding to the different lesion will be done

Inclusion Criteria:

• intestinal chronic inflammatory disease with at least one lesion such as hyperplasia or no dysplastic scalloped lesion, dysplastic scalloped lesion or low grade dysplasia or high grade dysplasia
• compliant patient
• endoscopic follow possible
• no settler cancer
• no serious pathology such as cancer

Exclusion Criteria:

• settler cancer
• serious pathology such as cancer
• no compliant patient
• endoscopic follow not possible