Safety and Efficacy of Nonsteroidal Antiinflammatory (NSAI)Drug and Glucocorticoids in Acute Sciatica

Safety and Efficacy of Nonsteroidal Antiinflammatory Drug and Glucocorticoids in Acute Sciatica

The purpose of this study is to determine whether anti-inflammatory drugs or glucocorticoids are effective in the treatment of acute sciatica

Inclusion Criteria:

• sciatica <8 weeks resistant to all treatments in ambulatory
• Acute low back pain> 48 hours;
• Non-deficit patients;
• Initial VAS> 40/100;
• Consent of patient
• Conflict disco-radicular concordance with the clinical computed tomography scan or magnetic resonance imaging.
• No of contraindications to methylprednisolone, ketoprofen;
• No registration to another protocol;

Exclusion Criteria:

• Pregnant, parturient, lactating mother;
• Diabetic patient;
• Patient with syndrome from narrowing of the lumbar vertebral canal
• Patient with a history of lumbar surgery <1 year;
• Patient with a Cauda equina syndrome or major motor disability;
• Crural neuralgia
• Patient with a deficit;
• Suspicion of sciatica secondary, ie not conflict-related disco-root: infectious neuritis, fracture on spinal bone tumor ...

associated treatment or pathology contra-indicating administration methylprednisolone, ketoprofen.