The Risk of Uncomplicated Peptic Ulcer in a Cohort of Secondary Prevention Aspirin Users
The Risk of Uncomplicated Peptic Ulcer in a Cohort of Secondary Prevention Aspirin Users
This study is conducted in a cohort of low dose aspirin (ASA) users previously ascertained. The aims of the post hoc analyses are:
To estimate the incidence of uncomplicated peptic ulcer (UPU) in a cohort of low-dose ASA for secondary prevention of vascular disease and the relative risk of UPU associated with use and discontinuation of use of low dose ASA.
To estimate the effect of proton pump inhibitors (PPI) on the occurrence of UPU among users of low-dose ASA for secondary prevention of vascular disease To evaluate the effect of other risk factors on the occurrence of UPU among users of low-dose ASA for secondary prevention of vascular disease.
The risk of uncomplicated peptic ulcer in a cohort of secondary prevention aspirin users
Inclusion Criteria:
- Patients aged 50-84 years in 2000-2007 with a first prescription of low dose ASA ( see study population description)
Exclusion Criteria:
- Patients aged below age 50 and 85 years and above ( see study population description)