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The purpose of this study is to evaluate the efficacy and the possible mechanisms underlying music-based multitask training (i.e., Jaques-Dalcroze eurhythmics) in older people, compared to multicomponent exercise training.
This study is designed as a 12-month, prospective, single-centre, single-blind, 2-arm, parallel group, randomized controlled trial in which 140 community-dwelling older adults at high risk of falls are randomly assigned to receive either a music-based multitask training intervention (i.e., Jaques-Dalcroze eurhythmics) or a multicomponent exercise training intervention, for 12 months. A 12-month follow-up is planned with outcome measures assessed at three time points: baseline (before intervention initiation), 6-month (intervention mid-point), and 12-month (intervention termination). Outcomes of interest include physical and cognitive performances, and falls. In addition, the investigators specifically address brain circuits in an exploratory sub-study. Volunteer trial participants from both study arms are invited to undergo functional magnetic resonance imaging (fMRI) at baseline and 12-month.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Jaques-Dalcroze eurhythmics training | Experimental | Once-weekly 60-min Jaques-Dalcroze eurhythmics class, for 12 months. |
|
| Multicomponent exercise training | Active Comparator | Once-weekly 60-min multicomponent exercise class supplemented by one 30-min home-based exercise session, for 12 months. |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Jaques-Dalcroze eurhythmics training | Behavioral | 12 months of weekly, supervised, structured, progressive, 60-min music-based multitask exercise classes (i.e., Jaques-Dalcroze eurhythmics). The music-based multitask program includes all exercises used in a previous work. |
| Measure | Description | Time Frame |
|---|---|---|
| Change in gait variability under dual-task condition | 6 months, 12 months |
| Measure | Description | Time Frame |
|---|---|---|
| Change in gait performances (quantitative gait analysis under single and dual-task conditions) | 6 months, 12 months | |
| Change in balance performances (quantitative balance analysis) | 6 months, 12 months |
| Measure | Description | Time Frame |
|---|---|---|
| Change in brain networks (structural and functional levels) | fMRI sub-study | 12 months |
Inclusion Criteria:
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Andrea Trombetti, MD | Bone Diseases Bone Diseases Service, Department of Internal Medicine Specialties, University Hospitals and Faculty of Medicine of Geneva | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Bone Diseases Service, Geneva University Hospitals | Geneva | 1211 | Switzerland |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 21098340 | Background | Trombetti A, Hars M, Herrmann FR, Kressig RW, Ferrari S, Rizzoli R. Effect of music-based multitask training on gait, balance, and fall risk in elderly people: a randomized controlled trial. Arch Intern Med. 2011 Mar 28;171(6):525-33. doi: 10.1001/archinternmed.2010.446. Epub 2010 Nov 22. |
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| Multicomponent exercise training | Behavioral | 12 months of weekly, i) supervised, structured, progressive, 60-min multicomponent exercise classes, supplemented by ii) 30-min home-based exercise sessions. Briefly, the multimodal exercise program is based on core components for successful fall prevention in older adults. It contains balance, gait, coordination and strength training, with balance as a core component. |
|
| Change in functional tests performances (Timed Up & Go test and Short Physical Performance Battery) | 6 months, 12 months |
| Incidence of falls and fractures (prospective daily recording using calendars, to be returned monthly) | 6 months, 12 months |
| Change in cognitive performances (comprehensive neuropsychological battery assessing different aspects of executive functioning) | 6 months, 12 months |
| Change in anxiety/depression (Hospital Anxiety and Depression scale) | 6 months, 12 months |
| Change in fear of falling (Short-FESI) | 6 months, 12 months |
| ID | Term |
|---|---|
| D009043 | Motor Activity |
| ID | Term |
|---|---|
| D001519 | Behavior |
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