Does Posterior Reconstruction of the Rhabdosphincter Improve Early Recovery of Continence After Robotic-Assisted Radical Prostatectomy?

Does the Posterior Reconstruction of the Rhabdosphincter Improve Early Recovery of Continence After Robotic-Assisted Radical Prostatectomy? A Multicenter Randomized Controlled Trial. A Phase III Open-label Prospective International Multicenter Randomized Controlled Study for the Evaluation of the Efficacy of PRR, in Patients Subjected to RALP, Measured in Terms of Early Recovery of the Continence.

The present study is a multicenter randomized, controlled trial, whose aim is to verify the effect of the posterior reconstruction of the rhabdosphincter after robot-assisted radical prostatectomy on early recovery of urinary continence.

Inclusion Criteria:

• Age ≥18 and ≤ 80 years;
• Biopsy proven clinically localized prostate cancer;
• Informed consent obtained and signed;
• Understanding of, and willingness to comply with, the study procedures.

Exclusion Criteria:

• Pre-operative incontinence;
• Salvage prostatectomy (defined as a prostatectomy prescribed after the failure of a different primary treatment);
• Surgical posterior plane at the peri - rectal fat, without preserving an edge of the Denonvilliers;
• History of psychiatric or addictive disorder or other medical condition that, in the opinion of the investigator, would preclude the patient from meeting the trial requirements;