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Low enrollment
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Test single nucleotide polymorphisms (SNP's) in ruptured and unruptured aneurysm tissue to identify a genetic difference between the two types of aneurysms; and to test SNP's in arteriovenous malformation tissue to identify a genetic link.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| AVM Patients | Patients receiving surgical intervention for an intracranial arterial-venous malformation. | ||
| Ruptured Aneurysm | Patients receiving surgical intervention for a ruptured intracranial aneurysm. | ||
| Unruptured Aneurysm | Patients receiving surgical intervention for an unruptured intracranial aneurysm. |
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| Measure | Description | Time Frame |
|---|---|---|
| Risk gene expression | The samples will be frozen after collection and then analyzed. | Within one week of sample collection. |
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Inclusion Criteria:
Exclusion Criteria:
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Patients admitted to University Hospital.
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| Name | Affiliation | Role |
|---|---|---|
| Eric M Deshaies, MD | SUNY Upstate Medical University Neurosurgery | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| SUNY Upstate Medical University | Syracuse | New York | 13210 | United States |
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Tissue samples of intracranial arterial-venous malformations (AVM) or aneurysm and blood samples.
| ID | Term |
|---|---|
| D001165 | Arteriovenous Malformations |
| D002532 | Intracranial Aneurysm |
| D013345 | Subarachnoid Hemorrhage |
| ID | Term |
|---|---|
| D054079 | Vascular Malformations |
| D018376 | Cardiovascular Abnormalities |
| D002318 | Cardiovascular Diseases |
| D014652 | Vascular Diseases |
| D000013 | Congenital Abnormalities |
| D009358 | Congenital, Hereditary, and Neonatal Diseases and Abnormalities |
| D020765 | Intracranial Arterial Diseases |
| D002561 | Cerebrovascular Disorders |
| D001927 | Brain Diseases |
| D002493 | Central Nervous System Diseases |
| D009422 | Nervous System Diseases |
| D000783 | Aneurysm |
| D020300 | Intracranial Hemorrhages |
| D006470 | Hemorrhage |
| D010335 | Pathologic Processes |
| D013568 | Pathological Conditions, Signs and Symptoms |
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