Air Pollution, Inflammation and Acute Coronary Syndrome

Impact of AIR Pollution on Inflammation, Oxidative Stress and 1-year Prognosis in Patients Hospitalized for Acute COronary Syndrome

The objectives of this study are: 1) To determine whether patients with acute coronary syndrome, the level of environmental exposure to particulate air pollutants in the week prior to admission, are related to concentrations of inflammatory molecules and oxidative stress. 2) To investigate whether the level of environmental exposure is an independent prognostic factor in terms of overall and cardiovascular mortality, myocardial infarction or unstable angina at 30 days, 6 and 12 months.

Inclusion Criteria:

• Patients with acute coronary syndrome

Exclusion Criteria:

• Infectious process and / or local or systemic inflammation in the 15 days before admission.
• Thyrotoxicosis.
• Neoplasms - or any other disease that seriously compromise the prognosis of life and / or generate a systemic inflammatory response.