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The purpose of this study is to determine the role of Proteomics and Metallomics in Cerebral Vasospasm following Subarachnoid Hemorrhage
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| SAH Patients | Patients admitted with the diagnosis of aneurismal subarachnoid hemorrhage (SAH) and cerebral angiogram negative SAH who would need to have the external ventricular drain (EVD) placed for the management of hydrocephalus. | ||
| Control Patients | Patients with non-hemorrhagic brain pathology such as posterior fossa tumor or stroke who will have the CSF sampling for diagnostic or therapeutic purposes. |
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| Measure | Description | Time Frame |
|---|---|---|
| Protein identification and concentration | For the duration of CSF drainage, or until the 21st day after admission. | |
| Metal ion identification and concentration | For the duration of CSF drainage, or until the 21st day after admission. |
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Inclusion Criteria:
Exclusion Criteria:
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Patients admitted to University Hospital.
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| Name | Affiliation | Role |
|---|---|---|
| Eric M Deshaies, MD | SUNY Upstate Medical University - Neurosurgery | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| State University of New York Upstate Medical University | Syracuse | New York | 13210 | United States |
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| ID | Term |
|---|---|
| D013345 | Subarachnoid Hemorrhage |
| D020301 | Vasospasm, Intracranial |
| D006849 | Hydrocephalus |
| ID | Term |
|---|---|
| D020300 | Intracranial Hemorrhages |
| D002561 | Cerebrovascular Disorders |
| D001927 | Brain Diseases |
| D002493 | Central Nervous System Diseases |
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Cerebrospinal Fluid (CSF)
| D009422 | Nervous System Diseases |
| D014652 | Vascular Diseases |
| D002318 | Cardiovascular Diseases |
| D006470 | Hemorrhage |
| D010335 | Pathologic Processes |
| D013568 | Pathological Conditions, Signs and Symptoms |