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| ID | Type | Description | Link |
|---|---|---|---|
| Dnr2013/41-32 | Other Identifier | Linkoping review board, Sweden |
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About 28 healthy subjects are randomized to 1 hour/day of coldprovocation or to the best of ability to avoid feeling cold, for 6 weeks. Basal metabolic rate and magnetic resonance (for determination of brown adipose tissue volume) imaging are performed before and after the study.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| cold provocation | Active Comparator | cold arm |
|
| to avoid feeling cold | Active Comparator | warm arm |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| cold arm | Procedure | 1 hour/day of cold provocation of such an extent that it is unpleasant but does not cause shivering |
|
| Measure | Description | Time Frame |
|---|---|---|
| Brown Adipose Tissue, Absolute Volume | Sub-clavicular brown adipose tissue volume by magnetic resonance imaging (liters) | Baseline and 6 week |
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Inclusion Criteria: healthy subjects -
Exclusion Criteria: any significant disease, ot other conditions that interferes with magnetic resonance imaging
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Faculty of Health Science, Linköping | Linköping | 58185 | Sweden |
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| ID | Title | Description |
|---|---|---|
| FG000 | Cold Provocation | cold arm cold arm: 1 hour/day of cold provocation of such an extent that it is unpleasant but does not cause shivering |
| FG001 | to Avoid Feeling Cold | warm arm warm arm: To the best of ability avoid feeling cold during 6 weeks |
| Title | Milestones | Reasons Not Completed | ||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Overall Study |
|
Healthy non-obese subjects
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| ID | Title | Description |
|---|---|---|
| BG000 | Cold Provocation | cold arm cold arm: 1 hour/day of cold provocation of such an extent that it is unpleasant but does not cause shivering |
| BG001 | to Avoid Feeling Cold | warm arm warm arm: To the best of ability avoid feeling cold during 6 weeks |
| Units | Counts |
|---|---|
| Participants |
|
| Title | Description | Population Description | Parameter Type | Dispersion Type | Unit of Measure | Calculate Percentage | Denominator Units Selected | Denominators | Classes |
|---|---|---|---|---|---|---|---|---|---|
| Age, Categorical | Count of Participants |
| Type | Title | Description | Population Description | Reporting Status | Anticipated Posting Date | Parameter Type | Dispersion Type | Unit of Measure | Calculate Percentage | Time Frame | Units Analyzed | Denominator Units Selected | Arm/Group Information | Denominators | Classes | Analyses | |||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Primary | Brown Adipose Tissue, Absolute Volume | Sub-clavicular brown adipose tissue volume by magnetic resonance imaging (liters) | Brown adipose tissue volume (liters) | Posted | Mean | Standard Deviation | liters | Baseline and 6 week |
|
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| ID | Title | Description | Deaths (Affected) | Deaths (At Risk) | Serious Events (Affected) | Serious Events (At Risk) | Other Events (Affected) | Other Events (At Risk) |
|---|---|---|---|---|---|---|---|---|
| EG000 | Cold Provocation | cold arm cold arm: 1 hour/day of cold provocation of such an extent that it is unpleasant but does not cause shivering no reported adverse events |
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| Title | Organization | Phone | Extension | |
|---|---|---|---|---|
| Fredrik H Nystrom | UHLinkopeing | +46101037749 | fredrik.h.nystrom@liu.se |
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| warm arm | Procedure | To the best of ability avoid feeling cold during 6 weeks |
|
| BG002 | Total | Total of all reporting groups |
| Participants |
|
| Age, Continuous | Continuous data was only available for those 14 participants who completed the study | because there were 14 who did the study | Mean | Standard Deviation | years |
|
| Sex: Female, Male | because 2 did not do the study at all | Count of Participants | Participants |
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| Region of Enrollment | Number | participants |
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| Units | Counts |
|---|---|
| Participants |
|
|
| 0 |
| 16 |
| 0 |
| 16 |
| EG001 | to Avoid Feeling Cold | warm arm warm arm: To the best of ability avoid feeling cold during 6 weeks | 0 | 12 | 0 | 12 |
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