Not provided
| ID | Type | Description | Link |
|---|---|---|---|
| R01HD072153 | U.S. NIH Grant/Contract | View source |
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
| Name | Class |
|---|---|
| University of Michigan | OTHER |
| Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) | NIH |
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
The increasing rate of obesity has become a major public health concern with national reports indicating 40% of African American adolescents are now overweight/obese. Little is known about effective weight loss interventions in ethnic minority adolescents. However, research has shown that ethnic minorities attend fewer intervention sessions, have higher attrition rates and lose less weight compared to Caucasians. Two fundamental problems related to this lack of progress are 1) lack of appropriate content of weight loss interventions for African American adolescents that integrate cultural issues, parenting skills, and motivational strategies for long-term change and, 2) poor dose of weight loss interventions because of participant fatigue and drop out. While previous weight loss studies for adolescents have been long lasting (12-25 weeks), our team developed a weight loss program that is a relatively brief (8-week) face-to-face intervention that integrates motivational (autonomy-support) and positive parenting skills (monitoring, social support, positive communication skills) for reducing z-BMI in overweight African American adolescents. Our team recently conducted a pilot study testing the feasibility of an 8-week on-line culturally tailored intervention, Thus, the goal of this project is to conduct a randomized controlled efficacy trial to address the problems with past studies by 1) making the face-to-face group intervention shorter, 2) using an on-line component to compliment the group-based intervention for increasing dose, and by 3) tailoring a motivational and parenting skills program directly to parents and adolescents skill levels and cultural background. 520 overweight African American adolescents and their parents will be recruited to participate. Phase I of the trial will test the efficacy of an 8-week face-to-face group randomized trial comparing motivational plus family-based weight loss (M+FWL) to a basic health (BH) education program on reducing z-BMI and improving diet and physical activity (PA) in overweight African American adolescents. In phase II of the trial participants will be re-randomized to either an 8-week on-line intervention or a control on-line program resulting in a 2 (M+FWL vs. BH group) x 2 (intervention vs. control on-line program) factorial design. A 6-month follow-up will examine whether adolescents in the 8-week M+FWL group plus 8-week on-line intervention program will show the greatest maintenance in reducing z-BMI.
Not provided
Not provided
Not provided
Not provided
Not provided
| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Mot. & Fam. Weight Loss + Online Interv. | Experimental | Participants are randomized to motivational and family weight loss program plus the online intervention. |
|
| Mot. & Fam. Weight Loss + Online Control | Experimental | Participants are randomized to motivational and family weight loss intervention and then the online control program. |
|
| Basic Health Educ. & Online Interv. | Experimental | Participants are randomized to the basic health education program and then the online intervention program. |
|
| Basic Health Educ. & Online Control | Active Comparator | Participants are randomized to the basic health education program and then to the online control program. |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Motivational and Family Weight Loss | Behavioral | This group will receive the comprehensive motivational and family weight loss intervention. |
|
| Measure | Description | Time Frame |
|---|---|---|
| Change in Body Mass Index (z-BMI) in Adolescents | We are investigating whether there is change in body mass index (BMI; age- and sex-adjusted based upon CDC norms) from baseline to 2 months and whether there are group differences (i.e., M+FWL vs. BH groups) in change in BMI in adolescents. | Baseline to 2 months |
| Change in Body Mass Index (z-BMI) in Adolescents | We are investigating whether there is change in body mass index (BMI; age- and sex-adjusted based upon CDC norms) from baseline to 4 months and whether there are group differences (i.e., M+FWL & Intervention online, M+FWL & Control online, BH & Intervention online, BH & Control online) in change in BMI in adolescents. | Baseline to 4 months |
| Change in Body Mass Index (z-BMI) in Adolescents | We are investigating intervention effects on change in body mass index (BMI; age- and sex-adjusted based upon CDC norms) from baseline to 6 months post-intervention. Specifically, we will examine whether there are group differences (i.e., M+FWL & Intervention online, M+FWL & Control online, BH & Intervention online, BH & Control online) in maintenance in BMI in adolescents. | Baseline to 6-month follow-up |
| Measure | Description | Time Frame |
|---|---|---|
| Change in Moderate to Vigorous Physical Activity (MVPA) in Parents and Adolescents | Minutes per day; We are investigating whether there is change of physical activity from baseline to 4 months and whether there are group differences (i.e., M+FWL & Intervention online, M+FWL & Control online, BH & Intervention online, BH & Control online) in change in MVPA in parents and adolescents. | Baseline to 4 months |
Not provided
Inclusion Criteria:
Exclusion Criteria:
Not provided
Not provided
Not provided
Not provided
Not provided
| Name | Affiliation | Role |
|---|---|---|
| Dawn K Wilson, PhD | University of South Carolina | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Obesity Research Group | Columbia | South Carolina | 29201 | United States |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 40374860 | Derived | Quattlebaum M, Sweeney AM, Wilson DK. Ecological predictors of family mealtime over time among overweight African American adolescent-parent dyads. J Behav Med. 2025 Aug;48(4):630-643. doi: 10.1007/s10865-025-00571-0. Epub 2025 May 15. | |
| 38460063 | Derived | Kipp C, Wilson DK, Brown A, Quattlebaum M, Loncar H, Sweeney AM, Abshire DA. Compounding effects of stress on diet, physical activity, and wellbeing among African American parents: a qualitative study to inform the LEADS health promotion trial. J Behav Med. 2024 Aug;47(4):647-661. doi: 10.1007/s10865-024-00477-3. Epub 2024 Mar 9. |
Not provided
Not provided
| Type | Date | Date Unknown |
|---|---|---|
| Release | Jan 17, 2023 | |
| Reset | Feb 13, 2023 | |
| Release | Jul 21, 2023 | |
| Reset | Aug 14, 2023 | |
| Release | Jun 4, 2025 | |
| Reset | Jun 23, 2025 | |
| Release | Sep 11, 2025 | |
| Reset | Sep 30, 2025 | |
| Release | May 18, 2026 | |
| Reset | Jun 12, 2026 |
Not provided
Not provided
| Release Date | Unrelease Date | Unrelease Date Unknown | Reset Date | MCP Release Number |
|---|---|---|---|---|
| Jan 17, 2023 | Feb 13, 2023 | |||
| Jul 21, 2023 |
| ID | Term |
|---|---|
| D050177 | Overweight |
| D009765 | Obesity |
| D009043 | Motor Activity |
| ID | Term |
|---|---|
| D044343 | Overnutrition |
| D009748 | Nutrition Disorders |
| D009750 | Nutritional and Metabolic Diseases |
| D001835 | Body Weight |
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
| Basic Health Education | Behavioral | This group will receive the comprehensive basic health education intervention. |
|
| Online Intervention | Behavioral | Participants will receive the online tailored weight loss intervention program after they have either received the motivational plus family weight loss program or basic health face-to-face program. |
|
| Online Control | Behavioral | Participants will receive the online control program after they have either received the motivational plus family weight loss program or the basic health education program. |
|
| Change of 24 Hour Dietary Recall (NDRS) of Kcals in Parents and Adolescents | We are investigating whether there is change of Kcals at 4 months. We are looking at these effects for fruit and vegetable intake, as well as total fat intake and whether there are group differences (i.e., M+FWL & Intervention online, M+FWL & Control online, BH & Intervention online, BH & Control online) in change in diet in parents and adolescents. | Baseline to 4 months |
| Change in Psychosocial Variables in Adolescents | Examine the effects of psychosocial variables (autonomy-support, monitoring, communication) as potential mediators of the intervention effects on changes in z-BMI, dietary intake, and MVPA in adolescents. | Baseline to 4 months |
| Change in Moderate to Vigorous Physical Activity in Adolescents | Minutes per day; We are investigating whether there is change of physical activity at the 6-month follow-up and whether there are group differences (i.e., M+FWL & Intervention online, M+FWL & Control online, BH & Intervention online, BH & Control online) in change in MVPA in adolescents. | Baseline to 6-month Follow-up |
| Change of 24 Hour Dietary Recall (NDRS) of Kcals in Adolescents | We are investigating whether there is change of Kcals at 6-month follow-up. We are specifically looking at effects for fruit and vegetable intake, as well as total fat intake in adolescents, and vegetable intake, as well as total fat intake and whether there are group differences (i.e., M+FWL & Intervention online, M+FWL & Control online, BH & Intervention online, BH & Control online) in change in diet in adolescents. | Baseline to 6-month Follow-up |
| Change in Body Mass Index (z-BMI) in Parents | We are investigating whether there is change in body mass index (BMI; age- and sex-adjusted based upon CDC norms) from baseline to 4 months and whether there are group differences (i.e., M+FWL & Intervention online, M+FWL & Control online, BH & Intervention online, BH & Control online) in change in BMI in parents. | Baseline to 4 months |
| Change in Body Mass Index (z-BMI) for Parents | We are investigating whether there is change in body mass index (BMI; age- and sex-adjusted based upon CDC norms) from baseline to 6 months and whether there are group differences (i.e., M+FWL & Intervention online, M+FWL & Control online, BH & Intervention online, BH & Control online) in change in BMI in parents. | Baseline to 6 Months Follow-up |
| 37043271 | Derived | Sweeney AM, Wilson DK, Resnicow K, Van Horn ML, Kitzman H. Engagement With Tailored Physical Activity Content: Secondary Findings From the Families Improving Together for Weight Loss Randomized Controlled Trial. J Med Internet Res. 2023 Apr 12;25:e42581. doi: 10.2196/42581. |
| 36260160 | Derived | Brown A, Wilson DK, Sweeney AM, van Horn ML, Zarrett N, Pate RR. Buffering effects of protective factors on light and moderate-to-vigorous physical activity among african american women. J Behav Med. 2023 Jun;46(3):405-416. doi: 10.1007/s10865-022-00360-z. Epub 2022 Oct 19. |
| 33751355 | Derived | Loncar H, Wilson DK, Sweeney AM, Quattlebaum M, Zarrett N. Associations of parenting factors and weight related outcomes in African American adolescents with overweight and obesity. J Behav Med. 2021 Aug;44(4):541-550. doi: 10.1007/s10865-021-00208-y. Epub 2021 Mar 9. |
| 33738484 | Derived | Kipp C, Wilson DK, Sweeney AM, Zarrett N, Van Horn ML. Effects of Parenting and Perceived Stress on BMI in African American Adolescents. J Pediatr Psychol. 2021 Aug 19;46(8):980-990. doi: 10.1093/jpepsy/jsab025. |
| 32692356 | Derived | Brown A, Wilson DK, Sweeney AM, Van Horn ML. The Moderating Effects of Social Support and Stress on Physical Activity in African American Women. Ann Behav Med. 2021 Apr 7;55(4):376-382. doi: 10.1093/abm/kaaa051. |
| 31126345 | Derived | Sweeney AM, Wilson DK, Loncar H, Brown A. Secondary benefits of the families improving together (FIT) for weight loss trial on cognitive and social factors in African American adolescents. Int J Behav Nutr Phys Act. 2019 May 24;16(1):47. doi: 10.1186/s12966-019-0806-5. |
| 30892641 | Derived | Wilson DK, Sweeney AM, Law LH, Kitzman-Ulrich H, Resnicow K. Web-Based Program Exposure and Retention in the Families Improving Together for Weight Loss Trial. Ann Behav Med. 2019 Mar 20;53(4):399-404. doi: 10.1093/abm/kay047. |
| 25835731 | Derived | Wilson DK, Kitzman-Ulrich H, Resnicow K, Van Horn ML, St George SM, Siceloff ER, Alia KA, McDaniel T, Heatley V, Huffman L, Coulon S, Prinz R. An overview of the Families Improving Together (FIT) for weight loss randomized controlled trial in African American families. Contemp Clin Trials. 2015 May;42:145-57. doi: 10.1016/j.cct.2015.03.009. Epub 2015 Mar 30. |
| Aug 14, 2023 |
| Jun 4, 2025 | Jun 23, 2025 |
| Sep 11, 2025 | Sep 30, 2025 |
| May 18, 2026 | Jun 12, 2026 |
| D012816 |
| Signs and Symptoms |
| D013568 | Pathological Conditions, Signs and Symptoms |
| D001519 | Behavior |