The Molecular Pathogenesis of Late-onset Fuchs' Endothelial Corneal Dystrophy

The Molecular Pathogenesis of Late-onset Fuchs' Endothelial Corneal Dystrophy

The purpose of this study is to gain further insights into the molecular pathogenesis of Fuchs' endothelial corneal dystrophy (FECD), to identify targets for potential specific drug therapy.

Inclusion Criteria:

• FECD
• normal corneas (including enucleations for uveal melanoma)
• non-FECD oedematous corneas

Exclusion Criteria:

• prior irradiation therapy for uveal melanoma
• corneal extension of uveal melanoma