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One of the aim of the neurosurgical treatment of brain tumor is to offer the maximal resection with the minimal neurological risk. The presurgical mapping of eloquent areas with functional magnetic resonance imaging (fMRI) is helpful to plan the surgery. BOLD fMRI is now the gold standard to map language areas. However, BOLD signal is diminished near the brain tumor. It is now possible to detect cortical activation with arterial spin labeling (ASL) techniques, detecting variations of perfusion during an activation paradigm (fASL), fASL could be interesting to detect eloquent areas near a brain tumor.
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| Measure | Description | Time Frame |
|---|---|---|
| Qualitative and quantitative comparison of brain activations obtained with both techniques (BOLD fMRI and fASL) | Qualitative and quantitative comparison of brain activations obtained with both techniques (BOLD fMRI and fASL) to presurgically detect language areas located near a brain tumor | 2 years |
| Measure | Description | Time Frame |
|---|---|---|
| Langage laterality index obtained with both techniques (BOLD fMRI and fASL)and fASL) | Size and location of activations obtained with BOLD fMRI and fASL in the presurgical detection of language areas | 2 years |
| Difference of cerebral blood flow maps obtained with ASL and fASL |
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Inclusion Criteria:
Exclusion Criteria:
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Patients with brain tumor involving MRI realization
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| Name | Affiliation | Role |
|---|---|---|
| Jean-Christophe Ferre | Rennes University Hospital | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Rennes University Hospital | Rennes | 35033 | France |
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| ID | Term |
|---|---|
| D001932 | Brain Neoplasms |
| ID | Term |
|---|---|
| D016543 | Central Nervous System Neoplasms |
| D009423 | Nervous System Neoplasms |
| D009371 | Neoplasms by Site |
| D009369 | Neoplasms |
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Cerebral blood flow quantification obtained with standard ASL and extracted from fASL |
| 2 years |
| D001927 |
| Brain Diseases |
| D002493 | Central Nervous System Diseases |
| D009422 | Nervous System Diseases |