This observational study will evaluate the efficacy and safety of Avastin (bevacizumab) in combination with fluoropyrimidine-based chemotherapy in elderly patients (>/= 65 years of age) with newly diagnosed metastatic colorectal cancer. Patients will be followed until disease progression, death, withdrawal of consent, discontinuation of physician-patient relationship or study closure, whichever comes first.

Inclusion Criteria:

• Adult patients, >/= 65 years of age
• Patients with newly diagnosed metastatic colorectal cancer starting first-line treatment with Avastin in combination with fluoropyrimidine-based chemotherapy according to the approved Hungarian Summary of Product Characteristics
• Patients suitable for Avastin treatment as assessed by the treating physician

Exclusion Criteria:

• Any contraindications to Avastin treatment according to the Hungarian Summary of Product Characteristics

Elderly patients (\