Compare the Efficacy of Mepilex and Keramatrix in Second Degree Burn Wounds

Prospective,Randomized, Parallel Study to Compare the Efficacy of Mepilex and Keramatrix in Promoting Healing of Second Degree Burn Wounds

The purpose of this study is to determine the extent to which Keramatrix dressing promotes the healing of second-degree burn wounds in pediatric patients.

Efficacy in promoting wound healing will be determined through comparison to Mepilex, an established burn wound dressing.

Inclusion Criteria:

patient age 0-18 years old Flame or scald burn 10-30% total body surface area burned Partial-thickness second-degree burns Admission within 72 hours of burn injury Clean non-infected wound as diagnosed by the attending physician

Exclusion Criteria:

• Patient older than 18
• Causes other than flame or scald injuries (ie.chemical or frostbite)
• Wounds noted to be contaminated or infected
• Patients who have received previous treatment efforts (topical dressings or previous wound debridement)
• Pregnancy lactation
• Co-morbidity which may compromise healing: known history of AIDS, ARC, HIV, cancer, autoimmune diseases,cirrhosis, tuberculosis, chronic glucocorticoid therapy, diabetes mellitus, renal insufficiency, hepatic disease, congestive heart failure prior to burn injury, associated severe head injury requiring specific treatment
• known allergy to sheep's wool