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| ID | Type | Description | Link |
|---|---|---|---|
| AAFC-WBANA | Other Grant/Funding Number | Agriculture & Agri-Food Canada |
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Essentially all of the published data on anthocyanin absorption in humans are from short term studies - a few days or less, most typically 24 h. However human studies demonstrating clinical effects are typically conducted for several weeks or even months. To examine how anthocyanin absorption and metabolism may be affected this study will examine urinary excretion of anthocyanins over one month, followed by a one week washout, and then one more dose of blueberry juice.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| anthocyanin-free diet | Other | Maintain anthocyanin-free diet throughout study. Day 1 to day 30, consume daily 250 ml single strength blueberry juice containing 229 mg anthocyanins, taken either as 1 morning dose or 1/3 dose morning, 1/3 mid-day and 1/3 evening. At d 31-38 continue anthocyanin-free diet. On d 39 consume daily dose. |
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| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Blueberry Juice | Other | Dietary intervention |
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| Measure | Description | Time Frame |
|---|---|---|
| Anthocyanins and Phase 2 anthocyanin conjugates in urine | 5 weeks |
| Measure | Description | Time Frame |
|---|---|---|
| White blood cell gene expression at start and end of study | 4 weeks |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Wilhelmina - Kalt, Ph.D. | Research Scientist | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Atlantic Food & Horticulture Research Centre | Kentville | Nova Scotia | B4N 1J5 | Canada |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 24432743 | Derived | Kalt W, Liu Y, McDonald JE, Vinqvist-Tymchuk MR, Fillmore SA. Anthocyanin metabolites are abundant and persistent in human urine. J Agric Food Chem. 2014 May 7;62(18):3926-34. doi: 10.1021/jf500107j. Epub 2014 Jan 27. |
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