Neuromuscular Ultrasound in ALS

Ultrasonography in Amyotrophic Lateral Sclerosis as a Predictor of Disease Progression and Tool in Diagnosis: a Pilot Study

Amyotrophic Lateral Sclerosis (ALS) is a progressive fatal neurodegenerative disease affecting motor neurons. Early diagnosis is essential for the success of clinical trials and objective biomarkers are needed for monitoring disease progression. Nerve and muscle ultrasound may provide this information.

This study will collect pilot data to evaluate the value of muscle and nerve ultrasound to identify and monitor disease progression in ALS.

Inclusion Criteria:

• Subjects referred to the electromyography laboratory for ALS.

Exclusion Criteria:

• Patients with known comorbid myopathy or neuropathy will be excluded from the study.
• Patients unable to provide their own consent will be excluded.