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Bright light therapy (BLT) has been found to be effective in treatment of seasonal affective disorder (SAD). The mechanism of action of conventional BLT in the treatment of SAD is under debate. Recently, transcranial bright light (TBL) via ear canals has been proved to modulate the neural networks of the human brain and improve cognitive performance in healthy subjects. Moreover, TBL has been found to alleviate symptoms of SAD in open trial. In this case the investigators will study the effect of transcranial bright light treatment via ear canals on depressive and anxiety symptoms in patients suffering from SAD in randomized controlled double-blind study design.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Transcranial bright light therapy | Experimental |
| |
| Transcranial placebo treatment | Placebo Comparator |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Transcranial bright light therapy | Device | The bright light treatment was given transcranially via ear canals by using bright light device. The bright light was produced using two light-emitting diodes (LEDs). The bright light was transmitted into both ear canals by an optical fibre. Daily 12 minutes TBL was taken at home during forenoon. |
| Measure | Description | Time Frame |
|---|---|---|
| Structured Interview Guide for the Hamilton Depression Rating Scale - Seasonal Affective Disorder Version Self Rating Version, total score ≤9 | Remission, i.e., Structured Interview Guide for the Hamilton Depression Rating Scale - Seasonal Affective Disorder Version Self Rating Version total score ≤ 9 | At the end of the four week study period |
| Measure | Description | Time Frame |
|---|---|---|
| Beck Depression Inventory-II, total score <=10 | Remission, i.e.,Beck Depression Inventory-II, total score <=10 | At the end of the four week study period |
| State Trait Anxiety Inventory -Y2, total score |
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Inclusion Criteria:
Exclusion Criteria:
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Oulu University | Oulu | Box 5000, 90014 | Finland |
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| ID | Term |
|---|---|
| D016574 | Seasonal Affective Disorder |
| ID | Term |
|---|---|
| D003866 | Depressive Disorder |
| D019964 | Mood Disorders |
| D001523 | Mental Disorders |
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| Transcranial placebo treatment | Device | The placebo treatment was given transcranially via ear canals by placebo device. Daily 12 minutes placebo treatment was taken at home during forenoon. |
|
| At the end of the four week study period |
| Trail- making test (TMT-A and TMT-B),total time | At the end of the four weeks study period |