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This will be a small study aimed at determining the effects of oral Immulina consumption on the immune system in elderly individuals.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Placebo | Placebo Comparator | 10 participants will be randomized to take 1 capsule of placebo daily. |
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| Immulina 200 mg/day | Experimental | 10 participants will be randomized to take 200 mg/day of Immulina. |
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| Immulina 400 mg/day | Experimental | 10 participants will be randomized to take 400 mg/day of Immulina. |
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| Immulina 800 mg/day | Experimental | 10 participants will be randomized to take 800 mg/day of Immulina. |
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| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Immulina | Dietary Supplement |
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| Measure | Description | Time Frame |
|---|---|---|
| Interferon gamma (IFNg) | Increase in IFNg from baseline to 8 weeks | 8 weeks |
| Measure | Description | Time Frame |
|---|---|---|
| Psychological Measures | Effects of Immulina on immune biomarkers based upon psychological differences including perceived stress, anxiety, depression and worry | 8 weeks |
| Optimal supplement regime |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Gailen D. Marshall, Jr., MD, PhD | University of Mississippi Medical Center | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| University of Mississippi Medical Center | Jackson | Mississippi | 39216 | United States |
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| ID | Term |
|---|---|
| C459207 | Immulina |
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Optimizing Immulina dose for maximal immune biomarker levels observing changes in Treg, Tr1, Th3, T Helper1, T Helper 2 cells, salivary cortisol, salivary alpha amylase, Interleukin 4 and Interleukin 10 cytokine production from baseline to 8 weeks
| 8 weeks |
| Demographic differences | Effects of Immulina based upon demographic differences including gender, race, age, BMI and socioeconomic status | 8 weeks |
| Immune biomarkers | Changes in Treg, Tr1, Th3, T Helper 1, T Helper 2 cells, salivary cortisol, salivary alpha amylase, Interleukin 4 and Interleukin 10 cytokine production from baseline to 8 weeks | 8 weeks |