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The Ulcerative Colitis (UC) belongs to the group of diseases called Inflammatory Bowel Disease (IBD) which is characterized by a chronic ulceration of the colon. The conventional treatment can have adverse effects and does not guarantee effectiveness in some patients requiring aggressive therapy using adjuvant therapy Aloe vera has been shown to have a beneficial effect in different disease, and have an anti-inflammatory effect in UC patients. Objective: Measuring the effect of the consumption of 200 ml of aloe vera gel daily for a period of three months, in the degree of inflammation in patients with mild UC based on Mayo scale and quantification of IL-6 in the colonic mucosa.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Aloe Vera | Experimental | Consume 200 ml of aloe vera gel per day over a period of three months |
|
| water | Placebo Comparator | Consume 200 ml of placebo per day over a period of three months |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Aloe Barbadensis Miller | Dietary Supplement |
| ||
| placebo water |
| Measure | Description | Time Frame |
|---|---|---|
| Full Mayo Score | 3 months | |
| Interleukine - 6 | Quantification in mucosal Biopsy | 3 months |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Jesús K. Yamamoto-Furusho, PhD,MD | Contact | +5554870900 | 2710 | kazuofurusho@hotmail.com |
| Name | Affiliation | Role |
|---|---|---|
| Jesús K Yamamoto-Furusho, MD, PhD | INCMNSZ | Study Chair |
| Lizzette C Alfaro | INCMNSZ | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| National Institute of Medical Science and Nutrition, Salvador Zubirán | Recruiting | D.f. | Tlalpan | 14000 | Mexico |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 22001864 | Background | Molodecky NA, Soon IS, Rabi DM, Ghali WA, Ferris M, Chernoff G, Benchimol EI, Panaccione R, Ghosh S, Barkema HW, Kaplan GG. Increasing incidence and prevalence of the inflammatory bowel diseases with time, based on systematic review. Gastroenterology. 2012 Jan;142(1):46-54.e42; quiz e30. doi: 10.1053/j.gastro.2011.10.001. Epub 2011 Oct 14. | |
| 21592901 |
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| ID | Term |
|---|---|
| D003093 | Colitis, Ulcerative |
| ID | Term |
|---|---|
| D003092 | Colitis |
| D005759 | Gastroenteritis |
| D005767 | Gastrointestinal Diseases |
| D004066 | Digestive System Diseases |
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|
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| D015212 |
| Inflammatory Bowel Diseases |
| D003108 | Colonic Diseases |
| D007410 | Intestinal Diseases |