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| ID | Type | Description | Link |
|---|---|---|---|
| R43TR000645 | U.S. NIH Grant/Contract | View source |
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| Name | Class |
|---|---|
| National Center for Advancing Translational Sciences (NCATS) | NIH |
| Michael Roman, PhD, LSSD | UNKNOWN |
| Ears of Texas, PA | UNKNOWN |
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The purpose of this study is to evaluate visual and nonvisual topographic memory impairment and its relationship to vestibular function in humans. Topographic memory refers to the ability to remember current and past locations in topographic (navigational) space and to make and/or adjust to spatial transformations using such memories. Performance on each of these topographic memory tasks will be compared to performance on a set of comparable nontopographic memory tasks. Topographic impairments represent some of the earliest cognitive deficits observed in Alzheimer's Disease, and the brain areas involved in topographic memory are the first to show degenerative changes.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Study Group |
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| Measure | Description | Time Frame |
|---|---|---|
| Determine relationship between topographic memory and vestibular function | 14 days |
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Inclusion Criteria:
Exclusion Criteria:
Other Restrictions:
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Nominally healthy adults between the ages of 70 and 85 yrs who meet inclusion/exclusion criteria. All study participants will be recruited from the San Antonio community.
| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Fred Previc, PhD | Contact | 210-308-0636 | fprevic@sbcglobal.net | |
| Karl McCloskey | Contact | (361) 442-7491 | mccloskey@biodevcorp.com |
| Name | Affiliation | Role |
|---|---|---|
| Fred Previc, PhD | Biomedical Development Corporation | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Ears of Texas, PA | San Antonio | Texas | 78215 | United States |
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| ID | Term |
|---|---|
| D000544 | Alzheimer Disease |
| ID | Term |
|---|---|
| D003704 | Dementia |
| D001927 | Brain Diseases |
| D002493 | Central Nervous System Diseases |
| D009422 | Nervous System Diseases |
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| Michael Roman, PhD, LSSP | San Antonio | Texas | 78229 | United States |
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| D024801 |
| Tauopathies |
| D019636 | Neurodegenerative Diseases |
| D019965 | Neurocognitive Disorders |
| D001523 | Mental Disorders |