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| ID | Type | Description | Link |
|---|---|---|---|
| S51079 | Other Identifier | Clinical Trial Centre UZ Leuven |
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Whole body MRI with diffusion weighted imaging is a useful imaging tool
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Indolent myeloma patient | |||
| Symptomatic Myeloma patient |
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| Measure | Description | Time Frame |
|---|---|---|
| Validation | Validation of whole body MRI diffusion-weighted imaging in multiple myeloma at 3 Tesla MRI: correlation of the new MRI imaging technique (diffusion weighted imaging)to standard validated imaging technique (Computer Tomography and Magnetic Resonance Imaging) | 2 years |
| Measure | Description | Time Frame |
|---|---|---|
| Therapy assessment | Whole body MRI with Diffusion weighted imaging is useful for treatment monitoring in multiple myeloma patients during and after therapy. Measurement of apparent diffusion coefficient (ADC) and comparison of ADC before, during and after therapy. Correlation of ADC with clinical findings and standard MRI findings. | 4 years |
| Measure | Description | Time Frame |
|---|---|---|
| outcome | correlation between early treatment response and outcome of the patient by measuring apparent diffusion coefficient | 5 years |
Inclusion Criteria:
Exclusion Criteria:
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Patients with clinical and laboratory findings, highly suggestive for multiple myeloma. All patients underwent bone marrow biopsy.
| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Steven Pans, MD | Contact | 3216340505 | steven.pans@uzleuven.be |
| Name | Affiliation | Role |
|---|---|---|
| Steven Pans, MD | Universitaire Ziekenhuizen KU Leuven | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| University Hospitals Leuven | Recruiting | Leuven | Belgium |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 22544292 | Background | Bannas P, Hentschel HB, Bley TA, Treszl A, Eulenburg C, Derlin T, Yamamura J, Adam G, Stubig T, Kroger N, Weber C. Diagnostic performance of whole-body MRI for the detection of persistent or relapsing disease in multiple myeloma after stem cell transplantation. Eur Radiol. 2012 Sep;22(9):2007-12. doi: 10.1007/s00330-012-2445-y. Epub 2012 Apr 29. |
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| ID | Term |
|---|---|
| D009101 | Multiple Myeloma |
| ID | Term |
|---|---|
| D054219 | Neoplasms, Plasma Cell |
| D009370 | Neoplasms by Histologic Type |
| D009369 | Neoplasms |
| D020141 | Hemostatic Disorders |
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| D014652 |
| Vascular Diseases |
| D002318 | Cardiovascular Diseases |
| D010265 | Paraproteinemias |
| D001796 | Blood Protein Disorders |
| D006402 | Hematologic Diseases |
| D006425 | Hemic and Lymphatic Diseases |
| D006474 | Hemorrhagic Disorders |
| D008232 | Lymphoproliferative Disorders |
| D007160 | Immunoproliferative Disorders |
| D007154 | Immune System Diseases |