A prostate cancer diagnosis starts a list of events that often leads to fast-moving treatment, thought by many to result in vast over-treatment of this disease. So, discovery of different diagnostic methods that allow clinicians to identify slow-growing from potentially fast-growing disease prior to or at the time of prostate biopsy could result in early and suitable treatment for men at greatest risk, while greatly decreasing the number of biopsies, surgical procedures, hormonal and chemotherapeutic treatments, cost, and patient worry, for those with more slow-growing disease.

Inclusion Criteria:

• Prostate cancer diagnosis prior to treatment
• Age 21 years or older
• Signed informed subject consent
• Prostatectomy as planned prostate cancer treatment

Exclusion Criteria:

• Men who do not choose prostatectomy
• Men who have undergone any neoadjuvant therapy
• Men who have cardiac pacemakers or other implanted electronic devices
• Men who have any surgically implanted metal
• Men who have had any surgical procedure that precludes placement of endorectal probe
• Indication of dementia or memory issues listed on problem list
• Men who indicate exposure to ocular metal fragments; confirmed by positive ocular x-ray
• Men who are taking newly-prescribed (within 6 months of enrollment) lipid control medications

all men newly-diagnosed with prostate cancer at the Portland VA and OHSU Urology clinics