Emollients in the Management of Atopic Dermatitis

Emollients in the Management of Atopic Dermatitis in Children: Prevention of Flares.

The purpose of this study is to confirm that emollients play a major role in the maintenance therapy after clearing of inflammatory lesions and can reduce occurrence of flares in children with atopic dermatitis.

Inclusion Criteria:

• Age between 2 and 6 years included,
• Presenting with atopic dermatitis, with at least one duly documented flare treated by corticosteroids within the previous 6 months, and presenting a current flare (objective Scoring for Atopic Dermatitis (SCORAD score) is [15-40] at inclusion),
• After treatment of the current flare, patients should have for randomization an Objective SCORAD score < 15, with Xerosis intensity≥ 1 and no subjective signs

Exclusion Criteria:

• Severe form of atopic dermatitis requiring either systemic corticosteroid treatment and/or antibiotic or antiviral treatment and/or hospitalisation,
• Primary bacterial, viral, fungal or parasitic skin infection,
• Ulcerated lesions, acne or rosacea,
• Dermatological disease other than atopic dermatitis which could interfere with the assessment,
• Immunosuppression,