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In the M-BRiHT study we aim to implement a programme of opportunistic HIV screening in the Emergency Department, Mater Misericordiae University Hospital. We hypothesize that such a programme will be acceptable in an Irish setting. We also wish to study the factors that influence test completion or acceptance. We will utilise informative interactive video media via a touch-screen tablet device to provide pre-test counselling and then offer rapid minimally invasive testing with a cotton-bud type swab of the buccal mucosa. In doing so we will to determine absolute numbers of those attending the ED who consent to watching the interactive information video about rapid HIV test screening. We will describe the absolute number and proportion of those who watch the interactive video who subsequently proceed to have the rapid HIV test. The primary aim is to determine the cultural, gender and ethnic factors which influence the completion of such rapid HIV testing with the future objective of maximising test completion in this crucial public health area.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| No participant choice of counselor | Experimental | Participants in this arm of the study are randomized to an interactive video counselor with no choice of counselor. This is delivered via a touchscreen tablet device. |
|
| Participant choice of counselor | Experimental | Participants in this arm of the study are randomized to an interactive video counselor with a choice of four different counselors. These gender and ethnically diverse counselors are delivered via a touchscreen tablet device. |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| No participant choice of counselor | Other | Participants in this arm of the study are randomized to an interactive video counselor with no choice of counselor. This is delivered via a touchscreen tablet device. |
| Measure | Description | Time Frame |
|---|---|---|
| Number of patients agreeing to undergo a HIV screening test in the Emergency Department | Establish a programme of HIV screening in the Emergency Department, Mater Misericordiae University Hospital. Acceptability of the programme will be judged in terms of absolute numbers of patients consenting to the test. | 24 months |
| Measure | Description | Time Frame |
|---|---|---|
| To determine the proportions of those who test negative who may fall in to the three month seroconversion window and to determine the proportion of those who return for repeat/multiple HIV tests at three months or other time in the future. | 24 months | |
| Absolute numbers of those attending the ED who consent to watching the interactive information video about rapid HIV test screening. |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Gerard S O'Connor, MB, MCEM | Contact | +353861732060 | geroconnor@me.com | |
| Patrick WG Mallon, MB,FRCPI,PhD | Contact | +35317166311 | Paddy.Mallon@ucd.ie |
| Name | Affiliation | Role |
|---|---|---|
| Patrick WG Mallon, MB, BCh, BAO, FRACP, FRCPI,PhD | Group Leader, HIV Molecular Research Group, University College Dublin | Principal Investigator |
| Gerard S O'Connor, MB, BCh, BAO, MCEM, MMed | Project Lead M-BRiHT, HIV Molecular Research Group, University College Dublin. |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Emergency Department, Mater Misericordiae University Hospital. | Recruiting | Dublin | Dublin 7 | Ireland |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 6265753 | Background | Centers for Disease Control (CDC). Pneumocystis pneumonia--Los Angeles. MMWR Morb Mortal Wkly Rep. 1981 Jun 5;30(21):250-2. No abstract available. | |
| 4234760 | Background | Wilson JM, Jungner YG. [Principles and practice of mass screening for disease]. Bol Oficina Sanit Panam. 1968 Oct;65(4):281-393. No abstract available. Spanish. |
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| ID | Term |
|---|---|
| D000163 | Acquired Immunodeficiency Syndrome |
| ID | Term |
|---|---|
| D015658 | HIV Infections |
| D000086982 | Blood-Borne Infections |
| D003141 | Communicable Diseases |
| D007239 | Infections |
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| Participant choice of counselor | Other | Participants in this arm of the study are randomized to an interactive video counselor with a choice of four different counselors. These gender and ethnically diverse counselors are delivered via a touchscreen tablet device. |
|
| 24 months |
| Absolute number and proportion of HIV positive test results | 24 months |
| CD4 count and viral load of newly diagnosed HIV positive patients | 24 months |
| Number of those testing positive who have acute seroconversion illness | 24 months |
| Study Director |
| Yvette Calderon, MD | Jacobi Medical Centre, New York | Study Director |
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| 16524549 | Background | Greenwald JL, Burstein GR, Pincus J, Branson B. A rapid review of rapid HIV antibody tests. Curr Infect Dis Rep. 2006 Mar;8(2):125-31. doi: 10.1007/s11908-006-0008-6. |
| 16988643 | Background | Branson BM, Handsfield HH, Lampe MA, Janssen RS, Taylor AW, Lyss SB, Clark JE; Centers for Disease Control and Prevention (CDC). Revised recommendations for HIV testing of adults, adolescents, and pregnant women in health-care settings. MMWR Recomm Rep. 2006 Sep 22;55(RR-14):1-17; quiz CE1-4. |
| 20577154 | Background | Centers for Disease Control and Prevention (CDC). Expanded HIV testing and trends in diagnoses of HIV infection - District of Columbia, 2004-2008. MMWR Morb Mortal Wkly Rep. 2010 Jun 25;59(24):737-41. |
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| D015229 |
| Sexually Transmitted Diseases, Viral |
| D012749 | Sexually Transmitted Diseases |
| D016180 | Lentivirus Infections |
| D012192 | Retroviridae Infections |
| D012327 | RNA Virus Infections |
| D014777 | Virus Diseases |
| D012897 | Slow Virus Diseases |
| D000091662 | Genital Diseases |
| D000091642 | Urogenital Diseases |
| D007153 | Immunologic Deficiency Syndromes |
| D007154 | Immune System Diseases |