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| ID | Type | Description | Link |
|---|---|---|---|
| 0556-12 | Other Identifier | TEL AVIV MEDICAL CENTER |
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This study will examine speech intelligibility of early parkinson's disease (PD) patients, early PD patients and first degree relatives. The investigators hypothesis that advanced PD patients will present decreased speech intelligibility more than early PD patients. Speech intelligibility of first degree relatives will be normal.
in order to achieve the study's goals objective and subjective research tools will be used.
Objective tools include measuring phonation time, diadokokinetic movements of the oral structures and acoustic analysis .
Subjective tools include self reported questionnaires.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| early & advanced PD 1st degree relatives | no intervention is performed in the study | ||
| recording speech and voice | no intervention(s) will be administered | ||
| speech intelligibility | no intervention(s) will be administered |
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| Measure | Description | Time Frame |
|---|---|---|
| Maximum phonation time | maximum phonation time will be measured after taking few measurements of sentence reading.It is an observational study that aim to collect data during DAY 1 only! day 1 for outcome measure time frames There are not pre/post measurements | DAY 1 |
| Measure | Description | Time Frame |
|---|---|---|
| Diadokokinetik (DDK): production time of 10x PATAKA, 7x /P/ and 7x /t/ | production time of 10x PATAKA, 7x /P/ and 7x /t/ will be measured during the examination. It is an observational study that aim to collect data during DAY 1 only! DAY 1 for outcome measure time frames There are not pre/post measurements | DAY 1 |
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Inclusion Criteria:A
Exclusion Criteria:
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Advanced PD patients Early PD patients First degree relatives
| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Tanya Gurevich, MD | Contact | 97236973061 | gurevich@tasmc.health.gov.il | |
| Yael Manor, PhD | Contact | 97236973061 | Yaelm@tasmc.health.gov.il |
| Name | Affiliation | Role |
|---|---|---|
| Tanya Gurevich, MD | Tel-Aviv Sourasky Medical Center | Principal Investigator |
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| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 16324824 | Background | Amir O, Ashkenazi O, Leibovitzh T, Michael O, Tavor Y, Wolf M. Applying the Voice Handicap Index (VHI) to dysphonic and nondysphonic Hebrew speakers. J Voice. 2006 Jun;20(2):318-24. doi: 10.1016/j.jvoice.2005.08.006. Epub 2005 Dec 1. |
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| ID | Term |
|---|---|
| D010300 | Parkinson Disease |
| ID | Term |
|---|---|
| D020734 | Parkinsonian Disorders |
| D001480 | Basal Ganglia Diseases |
| D001927 | Brain Diseases |
| D002493 | Central Nervous System Diseases |
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| D009422 | Nervous System Diseases |
| D009069 | Movement Disorders |
| D000080874 | Synucleinopathies |
| D019636 | Neurodegenerative Diseases |