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| Name | Class |
|---|---|
| Firma Rettenmeier & Söhne (Company) | UNKNOWN |
| German Center for Diabetes Research | OTHER |
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In animal models and retrospective studies, certain food components such as sugars and fiber have been detected as potential agents to influence development and progress of type 2 diabetes.
The DiNA study prospectively investigates, if non-soluble non-fermentable fibers (vs. soluble ones) and galactose (vs. palatinose) are capable to improvement metabolic parameters in patients with long-term type 2 diabetes and intensive insulin treatment.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| pure galactose | Active Comparator | 5 grams of galactose, three times a day with the main meals, duration: 4 weeks |
|
| pure palatinose | Placebo Comparator | 5 grams of palatinose, three times a day with the main meals, duration: 4 weeks |
|
| soluble non-fermentable fibers | Placebo Comparator | 5 grams of soluble non-fermentable fibers, three times a day with the main meals, duration: 4 weeks |
|
| non-soluble non-fermentable fibers | Active Comparator | 5 grams of non-soluble non-fermentable fibers, three times a day with each main meal, duration: 4 weeks |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Dietary supplement (4 arms, 2 active, 2 placebo) | Dietary Supplement |
|
| Measure | Description | Time Frame |
|---|---|---|
| metabolic improvement of type 2 diabetes | metabolic improvement of type 2 diabetes, as to be shown via hyperinsulinemic-euglycaemic clamp, mixed-meal test and daily demand of insulin units | 4 weeks |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Andreas F.H. Pfeiffer, Prof. Dr. med. | German Institute for Human Nutrition | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Charité-Klinikum Benjamin Franklin | Berlin | 12203 | Germany |
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| ID | Term |
|---|---|
| D003924 | Diabetes Mellitus, Type 2 |
| ID | Term |
|---|---|
| D003920 | Diabetes Mellitus |
| D044882 | Glucose Metabolism Disorders |
| D008659 | Metabolic Diseases |
| D009750 | Nutritional and Metabolic Diseases |
| D004700 | Endocrine System Diseases |
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| ID | Term |
|---|---|
| D019587 | Dietary Supplements |
| ID | Term |
|---|---|
| D005502 | Food |
| D000066888 | Diet, Food, and Nutrition |
| D010829 | Physiological Phenomena |
| D019602 | Food and Beverages |
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