A Pilot Study to Test the Safety and Feasibility of a Brillouin Ocular Analyzer

A Pilot Study to Test the Safety and Feasibility of a Brillouin Ocular Analyzer

A Brillouin ocular analyzer uses a low-power near infrared laser light to probe the viscoelastic properties of the cornea and crystalline lens in the eye. The study hypothesis is that the instrument can measure the Brillouin light scattering spectra from the eye safely and effectively from human subjects.

Inclusion Criteria:

• Healthy volunteers aged 20-60
• No refractional abnormalities
• Clear enough cornea and media to permit imaging

Exclusion Criteria:

• Occludable narrow angles (without a patent peripheral iridotomy)
• Other ocular or systemic pathology, which precludes safe eye dilation
• LASIK eye surgery
• Allergies to the dilation medication
• Only one healthy eye
• Pregnant women or expected pregnancy within the timeframe of the study
• Do not or cannot understand the instructions for the imaging
• Restricted mobility