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The purpose of the study is to evaluate the difference in Early Treatment Diabetic Retinopathy Study (ETDRS) visual acuity, oct retinal thickness and microperimetry in 2 groups of 30 eyes each affected by idiopathic epiretinal membranes that underwent phacoemulsification and 25G pars-plana vitrectomy with internal limiting membrane (ILM) peeling (Group 1) versus phacoemulsification only (Group 2), with a follow-up length up to 5 years.
Idiopathic epiretinal membranes represent a common cause of visual loss in elderly population. Vitrectomy with membrane peeling is nowadays considered the gold standard in the management of such pathology, with very good results either at short-time or at long-time follow up. In case of mild visual impairment due to epiretinal membrane and associated cataract, it is reasonable to treat only the lens pathology (with phacoemulsification and intra-ocular lens (IOL) implantation). In case of symptoms or ophthalmoscopic finding worsening it is always possible to submit patients who only underwent cataract surgery to vitrectomy with membrane peeling. There are, by now, no comparative studies between these two different approaches in medical literature.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| idiopathic epiretinal membranes | Experimental | Patients in first arm, with worse visual condition, treated with 25-G Vitrectomy and phacoemulsification (cataract intervention) |
|
| idiopathic epiretinal membrane | Active Comparator | Patient in second arm, with better pre-operative condition, treated with phacoemulsification (cataract intervention) only |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| 25-G vitrectomy and phacoemulsification | Procedure | 25-G vitrectomy with Internal Limiting Membrane peeling and phacoemulsification (cataract intervention) |
|
| Measure | Description | Time Frame |
|---|---|---|
| Visual acuity (using LogMar scale) changes from baseline to pre-defined periods after surgery | We observed how did the visual acuity (using LogMar scale) increase after the two different surgical approaches described. | within 90,180,360,1360 days after surgery |
| Measure | Description | Time Frame |
|---|---|---|
| Microperimetry parameters and average macular thickness changes | We evaluated average sensitivity (SM) and local defect (DL) using microperimetry. We also evaluated the average macular thickness using optical coherence tomography technology. | within 90,180,360,1360 days after surgery |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Marco Dal Vecchio, MD | Clinica Oculistica dell'Università , Ospedale Oftalmico Turin, Italy 10100 | Principal Investigator |
| Antonio M. Fea, MD, PhD | Clinica Oculistica dell'Università , Ospedale Oftalmico Turin, Italy | Study Chair |
| Carlo A Lavia, MD | Clinica Oculistica dell'Università , Ospedale Oftalmico Turin, Italy | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Clinica Oculistica dell'Università , Ospedale Oftalmico | Turin | 10100 | Italy |
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| phacoemulsification (cataract surgery) | Procedure | lens extraction after phacoemulsification and intra-ocular artificial lens implantation |
|
| ID | Term |
|---|---|
| D019773 | Epiretinal Membrane |
| ID | Term |
|---|---|
| D012164 | Retinal Diseases |
| D005128 | Eye Diseases |
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| ID | Term |
|---|---|
| D014821 | Vitrectomy |
| D018918 | Phacoemulsification |
| D002387 | Cataract Extraction |
| ID | Term |
|---|---|
| D013508 | Ophthalmologic Surgical Procedures |
| D013514 | Surgical Procedures, Operative |
| D054140 | Refractive Surgical Procedures |
| D059708 | Ultrasonic Surgical Procedures |
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