Arterial Stiffness in Chronic Kidney Disease

Diurnal Variations in Arterial Stiffness in Patients With Chronic Kidney Disease and Healthy Age Matched Controls

Diurnal variations in the cardiovascular system apparent in healthy individuals, are different in chronic kidney disease patients. Therefore, diurnal variations in arterial stiffness may also differ in chronic kidney disease patients. This study aims to identify and evaluate diurnal variations in arterial stiffness in chronic kidney disease patients and compare them to those in age matched healthy controls.

Inclusion Criteria:

• Systolic blood pressure <160 whether or not on antihypertensive medication
• diastolic blood pressure <100mmHg whether or not on antihypertensive medication
• Chronic kidney disease stage 2-5

Exclusion Criteria:

• Systolic blood pressure ≥160mmHg
• Diastolic blood pressure ≥100mmhg
• Significant comorbidity (investigator opinion but to include alcoholism and terminal illness)