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| ID | Type | Description | Link |
|---|---|---|---|
| PCTRatio Reevaluation | Other Identifier | CHIR-Net |
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Procalcitonin (PCT) serum levels are monitored in patients with secondary peritonitis after initial operative focus elimination to investigate the PCT ratio's impact on decision-making for or against early relaparotomy in the on-demand relaparotomy concept of secondary septic peritonitis.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| eliminated infectious abdominal focus | |||
| persisting/progressing infectious abdominal focus |
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| Measure | Description | Time Frame |
|---|---|---|
| prediction of focus elimination: cured patients versus patients with persisting peritonitis (definitions see below) | definition of 'focus elimination': patients with intestinal perforation or anastomotic leakage develop (local) peritonitis and consecutive abdominal sepsis. These patients need surgical intervention for focus elimination. This operative intervention aims to eradicate all infectious material and is intended to remove the leaking intestinal lesion. Whether this focus is eliminated or not can be controlled by either planned relaparotomy (normally within 48h after the first operation) or on demand relaparotomy in case of clinical deterioration. The focus can be assumed to be eliminated in all cases where either relaparotomy reveals no ongoing infection or persisting focus and whenever a patient recovers rapidly after initial surgery. | participants will be followed for the duration of hospital stay, an expected average of 21 days |
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Inclusion Criteria:
Exclusion Criteria:
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consecutive postoperative surgical patients on ICU after intestinal perforation or anastomotic leakage with indication for surgical focus elimination
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Klinikum rechts der Isar der TU München | Munich | Germany |
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| ID | Term |
|---|---|
| D010538 | Peritonitis |
| D018805 | Sepsis |
| ID | Term |
|---|---|
| D059413 | Intraabdominal Infections |
| D007239 | Infections |
| D010532 | Peritoneal Diseases |
| D004066 | Digestive System Diseases |
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| D018746 |
| Systemic Inflammatory Response Syndrome |
| D007249 | Inflammation |
| D010335 | Pathologic Processes |
| D013568 | Pathological Conditions, Signs and Symptoms |