Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
To detect by sonography relapse of disease activity prior to clinical symptoms in RA patients treated by rituximab.
Not provided
Not provided
Not provided
Not provided
Not provided
| Label | Type | Description | Intervention Names |
|---|---|---|---|
| rituximab | Experimental | Only one arm; all patients are treated by rituximab (monotherapy or in combination with conventional DMARD) |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| ESAOTE MyLab60 | Device | US evaluation at different time points |
|
| Measure | Description | Time Frame |
|---|---|---|
| global score of power-doppler activity measured by ultrasonography on 12 joints | Each time point will be assessed since the main objective of the study is to detect the time of sonographic relapse prior to clinical relapse | at 6 months after initiation of rituximab and then every 2 month over the follow-up period (18 months) |
Not provided
Not provided
Inclusion Criteria:
Exclusion Criteria:
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
| Name | Affiliation | Role |
|---|---|---|
| Olivier Vittecoq, MD,PHD | University Hospital, Rouen | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Department of Rheumatology, CHU de Caen | Caen | 14033 | France | |||
| Normandy |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 36377584 | Result | Vittecoq O, Kozyreff-Meurice M, Houivet E, Leon N, Berard L, Gauthier-Prieur M, Pouplin S, Avenel G, Brevet P, Benichou J, Michelin P, Marcelli C, Lequerre T. Clinical and ultrasonographic evaluation of the window of opportunity for retreatment with rituximab in rheumatoid arthritis patients from a multicentre real-life study. Clin Exp Rheumatol. 2023 May;41(5):1050-1058. doi: 10.55563/clinexprheumatol/zf8nnm. Epub 2022 Nov 12. |
Not provided
Not provided
Not provided
| ID | Term |
|---|---|
| D001172 | Arthritis, Rheumatoid |
| ID | Term |
|---|---|
| D001168 | Arthritis |
| D007592 | Joint Diseases |
| D009140 | Musculoskeletal Diseases |
| D012216 | Rheumatic Diseases |
Not provided
Not provided
| ID | Term |
|---|---|
| D014463 | Ultrasonography |
| D000069283 | Rituximab |
| ID | Term |
|---|---|
| D003952 | Diagnostic Imaging |
| D019937 | Diagnostic Techniques and Procedures |
| D003933 | Diagnosis |
| D058846 | Antibodies, Monoclonal, Murine-Derived |
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
| Rituximab | Drug |
|
| Caen, Le Havre, Rouen, Elbeuf |
| France |
| Department of Rheumatology | Le Havre | 76290 | France |
| Department of rheumatology | Rouen | 76031 | France |
| Department of Rheumatology CHG Elbeuf | Saint-Aubin-lès-Elbeuf | 76410 | France |
| D003240 |
| Connective Tissue Diseases |
| D017437 | Skin and Connective Tissue Diseases |
| D001327 | Autoimmune Diseases |
| D007154 | Immune System Diseases |
| D000911 | Antibodies, Monoclonal |
| D000906 | Antibodies |
| D007136 | Immunoglobulins |
| D007162 | Immunoproteins |
| D001798 | Blood Proteins |
| D011506 | Proteins |
| D000602 | Amino Acids, Peptides, and Proteins |
| D012712 | Serum Globulins |
| D005916 | Globulins |