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The purpose of this study is to further develop and test the Momentary Self-Monitoring and Feedback + Motivational Enhancement Therapy (MOMENT) intervention, a real-time, contextual intervention to reduce marijuana use among primary care patients.
This study proposes a pilot randomized trial to further develop and test the Momentary Self-Monitoring and Feedback + Motivational Enhancement Therapy (MOMENT) intervention, a real-time, contextual intervention to reduce marijuana use over three months in 15-to-24-year-old primary care patients who use frequently. We will randomize youth to one of two arms (goal 30 per arm completing 3-month follow-up): 1) MOMENT (MET + momentary self-monitoring + context-dependent feedback), or 2) MET-only. The two study arms will permit evaluation of the contributions of the self-monitoring and feedback components of the intervention above-and-beyond the MET and directly test the influence of the intervention on the link between momentary context and marijuana-related outcomes.
The specific aims of the study are
Specific Aim 1: Continued Feasibility Evaluation. In our preliminary work, we demonstrated that 1) youth perceive MOMENT to be easy to understand, comfortable, motivating, and helpful in reducing their marijuana use, 2) we can recruit 4 participants/month (minimum rate for the proposed study), and 3) we can successfully implement a MOMENT intervention study in the proposed recruitment sites. Based on this work, we have identified additional areas of feasibility on which to focus in the proposed study. Specifically, we aim to achieve:
1a. A signal response rate of at least 70% during each of three periods of momentary data collection - baseline, intervention, and 3-month follow-up.
1b. A diary response rate of at least 70% during each momentary data collection period
c. A retention rate of at least 80% of participants at the 3-month follow-up.
Specific Aim 2. Early-Stage Efficacy Exploration. Our preliminary work showed that both momentary and individual-level outcomes improved from baseline to three months post-intervention. The primary momentary outcomes are desire to use marijuana when in a triggering context and likelihood of use following exposure to a triggering context. The primary individual-level outcomes are number of use events/week, 30-day percent of days abstinent, dose/use event, and measures of motivation (importance of, readiness for, and confidence about reducing use). Based on the preliminary findings, we will explore these early-stage efficacy questions:
a. Will improvements in momentary outcomes be observed with MOMENT, but not MET-only?
(1) The association between exposure to self-identified trigger contexts and momentary desire to use marijuana will be attenuated at three months, compared to pre-intervention.
(2) The likelihood of marijuana use following exposure to a trigger context will be reduced at three months.
2b. Will improvements in individual-level outcomes be greater with MOMENT vs. MET-only?
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| MET only | Active Comparator | Motivational Enhancement Therapy only |
|
| MOMENT | Experimental | The full MOMENT intervention: Motivational Enhancement Therapy + momentary and daily mobile self-monitoring + motivational feedback messages prompting participants to consider their individualized coping strategies to avoid using marijuana |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| MET | Behavioral | Motivational Enhancement Therapy only |
|
| Measure | Description | Time Frame |
|---|---|---|
| Marijuana desire | Desire to use marijuana when in top-3 trigger context | 3 months |
| Marijuana use following trigger exposure | Marijuana use following exposure to top-3 trigger context | 3 months |
| Frequency of marijuana use | Marijuana use events/day | 3 months |
| Percent days abstinent | 30-day percent days abstinent from marijuana use | 3 months |
| Motivation to reduce marijuana use | Daily score on 3 scales - readiness to reduce marijuana use, importance of reducing use, and confidence in ability to reduce use | 3 months |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Lydia A Shrier, MD, MPH | Boston Children's Hospital | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Boston Children's Hospital Adolescent/Young Adult Medical Clinic | Boston | Massachusetts | 02115 | United States | ||
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 36272891 | Derived | Shrier LA, Harris SK. Associations of Momentary Mindfulness With Affect and Cannabis Desire in a Trial of Cannabis Use Interventions With and Without Momentary Assessment. J Adolesc Health. 2023 Jan;72(1):126-129. doi: 10.1016/j.jadohealth.2022.09.002. Epub 2022 Oct 20. |
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| ID | Term |
|---|---|
| D002189 | Marijuana Abuse |
| ID | Term |
|---|---|
| D019966 | Substance-Related Disorders |
| D064419 | Chemically-Induced Disorders |
| D001523 | Mental Disorders |
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| ID | Term |
|---|---|
| D062405 | Motivational Interviewing |
| ID | Term |
|---|---|
| D037001 | Directive Counseling |
| D003376 | Counseling |
| D008605 | Mental Health Services |
| D004191 | Behavioral Disciplines and Activities |
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| MOMENT | Behavioral | The full MOMENT intervention: Motivational Enhancement Therapy + momentary and daily mobile self-monitoring + motivational feedback messages prompting participants to consider their individualized coping strategies to avoid using marijuana |
|
| Martha Eliot Health Center Adolescent Clinic |
| Jamaica Plain |
| Massachusetts |
| 02130 |
| United States |
| D006296 | Health Services |
| D005159 | Health Care Facilities Workforce and Services |