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Unable to recruit sufficient number of subjects in required timeline.
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| Name | Class |
|---|---|
| University Hospital, Geneva | OTHER |
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Ocular hypertension and glaucoma are eye conditions associated with abnormally high fluid pressure in the eye (called intraocular pressure or IOP). If left untreated, the elevated IOP may eventually cause damage to the nerve of the eye and potential impairment of vision.
The use of certain drugs has been identified as a risk factor for raised IOP, including various forms of administration of corticosteroids. Corticosteroids can also lead to cataract, which is clouding of the lens in the eye that can affect vision.
In this research study, we would like to find out whether the use of corticosteroids in our dermatology clinic leads to raised IOP, in order to identify patients at risk and to allow them to be more closely monitored than others. It is important to identify those patients who have a corticosteroid-induced pressure rise early enough to prevent them from permanent glaucomatous visual loss.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Potent topical steroid-treated | Patients treated with potent topical steroids |
| |
| Superpotent topical steroid-treated | Patients treated with superpotent topical steroids |
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| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Potent topical steroid | Drug |
| ||
| Superpotent topical steroid |
| Measure | Description | Time Frame |
|---|---|---|
| Change in intraocular pressure from baseline | Measurements will be done at 28 (+/- 7 days) days, 56 (+/- 7 days) days, and 90 (+/- 7 days)days after initiation of topical steroids. | after 1, 2 and 3 months |
| Measure | Description | Time Frame |
|---|---|---|
| Whether there is any clinical evidence of cataract at the final visit of the study. | Measurements will be done at 28 (+/- 7 days) days, 56 (+/- 7 days) days, and 90 (+/- 7 days)days after initiation of topical steroids. | After 1, 2 and 3 months |
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Inclusion Criteria:
Exclusion Criteria:
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Dermatology clinic
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| University Hospitals Coventry and Warwickshire NHS Trust | Coventry | West Midlands | CV2 2DX | United Kingdom |
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| Drug |
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