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Recent reports have described cases of novel thin-strut coronary stent longitudinal deformation during or after deployment and a biomechanical analysis have suggested increased susceptibility for such a complication for the platinum chromium (PtCr) coronary stent platforms . This analysis aims to assess the incidence of longitudinal stent deformation for PtCr stents in a large single centre all-comers population using quantitative angiographic analysis (QCA).
Aims: Recent reports have described cases of novel thin-strut coronary stent longitudinal deformation during or after deployment and a biomechanical analysis have suggested increased susceptibility for such a complication for the platinum chromium (PtCr) coronary stent platforms .
The aim of this analysis is to assess the incidence of longitudinal stent deformation for PtCr stents in a large single centre all-comers population .
Methods: Quantitative angiographic analysis (QCA) of PtCr stents deployed in consecutive all-comers patients treated in our Laboratory from January 2011 to August 2012 will be performed by an independent core laboratory. In particular QCA : nominal stent lenght ratio will be calculated for every PtCr stent.
Clinical follow up with data about overall and cardiac mortality, myocardial infarction and target vessel revascularization will also be performed.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| PtCr stent PCI treated patients | patients treated with PCI in whichat least 1 PtCr stent was used |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| coronary angioplasty with PtCr stent implantation | Device | PCI with deployment of at least 1 PtCr stent |
|
| Measure | Description | Time Frame |
|---|---|---|
| QCA : nominal stent lenght ratio | QCA measured lenght of the deployed stent divided for the nominal stent lenght, a surrogate marker for stent deformation | 1 day |
| Measure | Description | Time Frame |
|---|---|---|
| cardiovascular mortality | death from cardiac or vascular causes | 1 year |
| myocardial infarction | recurring myocardial infarction (MI), according to the novel 3rd definition of MI |
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Inclusion Criteria:
Exclusion Criteria:
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253 consecutive all-comers patients treated in our Laboratory from January 2011 to August 2012 with PCI using a platinum-chromium platform based DES
| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Alessandro Lupi, M.D. | Contact | 0039 0321 3733236 | lupialessandro1@tin.it |
| Name | Affiliation | Role |
|---|---|---|
| Alessandro Lupi, MD | AO Maggiore della Carita | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Ospedale Maggiore della Carità | Recruiting | Novara | Piedmont | 28100 | Italy |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 24993987 | Derived | Lupi A, Porto I, Rognoni A, Lazzero M, Fattori R, Parisi R, De Maria GL, Bongo AS, Sheiban I, Bolognese L, Agostoni P, Secco GG; Novara-PROMETEUS (Platinum ChROMium Everolimus EluTing StEnt SpontaneoUs RegiStry) Investigators. Clinical and biomechanical behavior of a platinum-chromium stent platform in a large all-comer single-center population: insights from the Novara-PROMETEUS registry. J Invasive Cardiol. 2014 Jul;26(7):311-7. |
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| ID | Term |
|---|---|
| D009203 | Myocardial Infarction |
| ID | Term |
|---|---|
| D017202 | Myocardial Ischemia |
| D006331 | Heart Diseases |
| D002318 | Cardiovascular Diseases |
| D014652 | Vascular Diseases |
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| ID | Term |
|---|---|
| D000800 | Angioplasty, Balloon |
| ID | Term |
|---|---|
| D017130 | Angioplasty |
| D002404 | Catheterization |
| D013812 | Therapeutics |
| D057510 | Endovascular Procedures |
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| 1 year |
| target vessel failure | any clinically-driver revascularization of the treated coronary vessel | 1 year |
| Macroscopical stent deformation | severe stent deformation after deployment or other interventional manouvres (postdilation, IVUS, etc.) | 1 day |
| D007238 |
| Infarction |
| D007511 | Ischemia |
| D010335 | Pathologic Processes |
| D013568 | Pathological Conditions, Signs and Symptoms |
| D009336 | Necrosis |
| D014656 |
| Vascular Surgical Procedures |
| D013504 | Cardiovascular Surgical Procedures |
| D013514 | Surgical Procedures, Operative |
| D019060 | Minimally Invasive Surgical Procedures |
| D008919 | Investigative Techniques |