The Difference in Cerebral Oxygenation Between Propofol and Sevoflurane

The Difference in Cerebral Oxygenation Between Propofol and Sevoflurane

the purpose of this study is to investigate whether propofol and sevoflurane have difference effect on cerebral oxygenation .

the purpose of this study:(1) to investigate the incidence of preoperative cerebral oxygenation abnormity (SjvO2 <55%) and its relationship with intraoperative cerebral desaturation and POCD. (2) To investigate the change of intraoperative cerebral oxygen supply and demand balance and the incidence of cerebral desaturation in patients with abnormal preoperative cerebral oxygenation during sevoflurane anesthesia. (3)To investigate the incidence of early POCD in patients with abnormal preoperative cerebral oxygenation during sevoflurane and propofol anesthesia.

Inclusion Criteria:

• scheduled to take major surgery under general anesthesia over 18 years old classified as ASA class three or less

Exclusion Criteria:

• have a diagnosis of cerebrovascular disorder