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Safety and Efficacy of Ginsenoside Rg3 in Combination with First-line Chemotherapy in Advanced Gastric Cancer.The purpose of this study is to assess the safety of Ginsenoside Rg3 in advanced gastric cancer, and whether it improves the efficacy of first-line chemotherapy.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| experimental | Experimental | Ginsenoside Rg3 plus First-line Chemotherapy |
|
| Active Comparator | Active Comparator | First-line Chemotherapy |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Ginsenoside Rg3 plus First-line Chemotherapy | Drug | Ginsenoside Rg3 20mg 2/day po,patients will receive Ginsenoside Rg3 until progression XELOX(oxaliplatin 130mg/m2 iv d1;capecitabine 1000mg/m2 po bid d1-14)every 3 weeks for 4 cycles followed by capecitabine until progression |
| Measure | Description | Time Frame |
|---|---|---|
| Progression-free survival (PFS) | 1 years |
| Measure | Description | Time Frame |
|---|---|---|
| Objective Response Rate (ORR) | 1 year | |
| Overall Survival (OS) | 3 year |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Baoen Shan | Contact | 15931166600 | 15931166600@126.com |
| Name | Affiliation | Role |
|---|---|---|
| Wei Liu | Hebei Tumor Hospital | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Hebei Tumor Hospital | Recruiting | Shijiazhuang | Hebei | 050011 | China |
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| ID | Term |
|---|---|
| C097367 | ginsenoside Rg3 |
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| First-line Chemotherapy | Drug | XELOX(oxaliplatin 130mg/m2 iv d1;capecitabine 1000mg/m2 po bid d1-14)every 3 weeks for 4 cycles followed by capecitabine until progression |
|