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Unable to continue study due to time constraints
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Effect of dexamethasone on prolonging upper extremity block is well known. But it not known if the effect comes from its local effect on the nerves or from its general analgesic effect. In this study we will compare the systemic effect to its local effect to find out if there is a difference or not.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Bupivacaine | Active Comparator | Control |
|
| Bupivacaine with Dexamethasone | Experimental | Dexamethasone will be mixed with bupivacaine |
|
| Intravenous Dexamethasone | Active Comparator | Dexamethasone will be given intravenously |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Dexamthsone | Drug |
| ||
| Bupivacaine |
| Measure | Description | Time Frame |
|---|---|---|
| Analgesia Duration | 72 hrs |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Tariq Malik, MD | University of Chicago | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| University of Chicago Medical Center | Chicago | Illinois | 60637 | United States |
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| ID | Title | Description |
|---|---|---|
| FG000 | Bupivacaine | Control Bupivacaine |
| FG001 | Bupivacaine With Dexamethasone | Dexamethasone will be mixed with bupivacaine Dexamthsone Bupivacaine |
| FG002 | Intravenous Dexamethasone | Dexamethasone will be given intravenously Dexamthsone Bupivacaine |
| Title | Milestones | Reasons Not Completed | ||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Overall Study |
|
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| ID | Title | Description |
|---|---|---|
| BG000 | Bupivacaine | Control Bupivacaine |
| BG001 | Bupivacaine With Dexamethasone | Dexamethasone will be mixed with bupivacaine Dexamthsone Bupivacaine |
| Units | Counts |
|---|---|
| Participants |
|
| Title | Description | Population Description | Parameter Type | Dispersion Type | Unit of Measure | Calculate Percentage | Denominator Units Selected | Denominators | Classes |
|---|---|---|---|---|---|---|---|---|---|
| Age, Categorical | Count of Participants |
| Type | Title | Description | Population Description | Reporting Status | Anticipated Posting Date | Parameter Type | Dispersion Type | Unit of Measure | Calculate Percentage | Time Frame | Units Analyzed | Denominator Units Selected | Arm/Group Information | Denominators | Classes | Analyses | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Primary | Analgesia Duration | study terminated prematurely due to lack of resources and participation- no data collected for Outcome measures and no analysis done | Posted | 72 hrs |
|
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| ID | Title | Description | Deaths (Affected) | Deaths (At Risk) | Serious Events (Affected) | Serious Events (At Risk) | Other Events (Affected) | Other Events (At Risk) |
|---|---|---|---|---|---|---|---|---|
| EG000 | Bupivacaine | Control Bupivacaine |
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| Title | Organization | Phone | Extension | |
|---|---|---|---|---|
| TARIQ MALIK | University of Chicago | 773-8342643 | tmalik@dacc.uchicago.edu |
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| ID | Term |
|---|---|
| D000377 | Agnosia |
| ID | Term |
|---|---|
| D010468 | Perceptual Disorders |
| D019954 | Neurobehavioral Manifestations |
| D009461 | Neurologic Manifestations |
| D009422 | Nervous System Diseases |
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| ID | Term |
|---|---|
| D002045 | Bupivacaine |
| ID | Term |
|---|---|
| D000813 | Anilides |
| D000577 | Amides |
| D009930 | Organic Chemicals |
| D000814 | Aniline Compounds |
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| Drug |
|
| BG002 | Intravenous Dexamethasone | Dexamethasone will be given intravenously Dexamthsone Bupivacaine |
| BG003 | Total | Total of all reporting groups |
| Participants |
|
| Sex/Gender, Customized | Count of Participants | Participants |
|
| Region of Enrollment | Count of Participants | Participants |
|
|
| 0 |
| 3 |
| 0 |
| 3 |
| EG001 | Bupivacaine With Dexamethasone | Dexamethasone will be mixed with bupivacaine Dexamthsone Bupivacaine | 0 | 1 | 0 | 1 |
| EG002 | Intravenous Dexamethasone | Dexamethasone will be given intravenously Dexamthsone Bupivacaine | 0 | 1 | 0 | 1 |
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| D012816 | Signs and Symptoms |
| D013568 | Pathological Conditions, Signs and Symptoms |
| D000588 |
| Amines |