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Corneal lesions such as corneal abrasions and corneal infiltrates are common in clinical practice. The current study seeks to investigate whether high-resolution OCT is suitable for imaging of these corneal lesions. The present study has the character of a pilot study and the results are intended to be used to develop a standardized protocol for imaging and analysis of these corneal lesions. Based on this protocol, further studies investigating the pathophysiology of corneal lesions or evaluating therapeutic success can be planned.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| 10 patients with corneal abrasions | Experimental |
| |
| 10 patients with corneal infiltrates | Experimental |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Optical Coherence Tomography (OCT) | Device | High-resolution OCT imaging of the cornea |
|
| Measure | Description | Time Frame |
|---|---|---|
| Imaging of corneal abrasions and infiltrates | The aim of this pilot study is to investigate whether imaging of these corneal alterations is possible. | 1 day |
| Measure | Description | Time Frame |
|---|---|---|
| Size and depth of corneal lesions as assessed with high-resolution OCT | The volume and size of corneal lesions or infiltrates will be assessed using a specific software. | 1 day |
| Slit lamp biomicroscopy with fluorescein staining |
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Inclusion Criteria:
Exclusion Criteria:
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Department of Clinical Pharmacology, Medical University of Vienna | Vienna | 1090 | Austria |
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| ID | Term |
|---|---|
| D065306 | Corneal Injuries |
| ID | Term |
|---|---|
| D005131 | Eye Injuries |
| D005151 | Facial Injuries |
| D006259 | Craniocerebral Trauma |
| D020196 | Trauma, Nervous System |
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| ID | Term |
|---|---|
| D041623 | Tomography, Optical Coherence |
| D066167 | Slit Lamp |
| ID | Term |
|---|---|
| D041622 | Tomography, Optical |
| D061848 | Optical Imaging |
| D003952 | Diagnostic Imaging |
| D019937 | Diagnostic Techniques and Procedures |
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| Slit lamp biomicroscopy | Other | Slit lamp biomicroscopy with fluorescein staining and slit lamp photograph |
|
The volume and size of corneal lesions or infiltrates will be assessed.
| 1 day |
| D009422 |
| Nervous System Diseases |
| D003316 | Corneal Diseases |
| D005128 | Eye Diseases |
| D014947 | Wounds and Injuries |
| D003933 | Diagnosis |
| D014054 | Tomography |
| D008919 | Investigative Techniques |
| D019721 | Ophthalmoscopes |
| D019719 | Diagnostic Equipment |
| D004864 | Equipment and Supplies |