Can Fish Oil and Phytochemical Supplements Mimic Anti-Aging Effects of Calorie Restriction?

Can Fish Oil and Phytochemical Supplements Mimic Anti-Aging Effects of Calorie Restriction?

The purpose of this study is to determine if a combination of 10 nutritional supplements provide health benefits that are consistent with protection against age-related disease. All supplements have been shown in previous studies to have health benefits when administered alone. The hypothesis is that 6 months of taking 10 nutritional supplements each day will provide beneficial changes in healthy related measures.

Inclusion Criteria:

• age 40-60 yr
• body mass index of 21 - 30 kg/m2
• sedentary to moderately active
• eating a typical US diet

Exclusion Criteria:

• history of any chronic disease other than mild osteoarthritis
• use of medications other than occasional use of non-steroidal anti-inflammatory drugs, antihistamines, antacids or laxatives
• use of nutritional supplements
• smoking
• alcohol intake greater than two drinks per day for women and three drinks per day for men