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This exploratory cross-sectional study proposes, firstly, to objectify in a population of Charcot-Marie-Tooth disease type 1A (CMT 1A)if there is a correlation between the recording of electrical parameters and upper limb muscle strength of the thigh and in a second step, to seek a relationship between the measured parameters.
Patients suffering from CMT 1A neuropathy will be invited to go through a series of tests such as:
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| Measure | Description | Time Frame |
|---|---|---|
| axonal loss | at day 1 |
| Measure | Description | Time Frame |
|---|---|---|
| Muscle strength | at day 1 | |
| Functional scores | at day 1 | |
| Hand testing |
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Inclusion Criteria:
Exclusion Criteria:
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Patients suffering from CMT 1A neuropathy
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| Name | Affiliation | Role |
|---|---|---|
| Emmanuel COUDEYRE | University Hospital, Clermont-Ferrand | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| CHU Clermont-Ferrand | Clermont-Ferrand | 63003 | France |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 31255638 | Derived | Bihel L, Reynaud V, Givron P, Clavelou P, Cornut-Chauvinc C, Pereira B, Thomas E, Taithe F, Coudeyre E. Foot Function Index: A Promising Questionnaire for Individuals With Charcot-Marie-Tooth Disease Type 1A. Arch Phys Med Rehabil. 2019 Dec;100(12):2403-2406. doi: 10.1016/j.apmr.2019.06.003. Epub 2019 Jun 28. |
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| at day 1 |
| spatial and temporal parameters of walking | at day 1 |
| Barometric stabilometric podo-static scores | at day 1 |
| Quality of life | at day 1 |
| Fatigue | at day 1 |
| Depression | at day 1 |
| ID | Term |
|---|---|
| D002607 | Charcot-Marie-Tooth Disease |
| ID | Term |
|---|---|
| D015417 | Hereditary Sensory and Motor Neuropathy |
| D009421 | Nervous System Malformations |
| D009422 | Nervous System Diseases |
| D020271 | Heredodegenerative Disorders, Nervous System |
| D019636 | Neurodegenerative Diseases |
| D011115 | Polyneuropathies |
| D010523 | Peripheral Nervous System Diseases |
| D009468 | Neuromuscular Diseases |
| D000013 | Congenital Abnormalities |
| D009358 | Congenital, Hereditary, and Neonatal Diseases and Abnormalities |
| D030342 | Genetic Diseases, Inborn |
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