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| Name | Class |
|---|---|
| Société des Produits Nestlé (SPN) | INDUSTRY |
| Baxter S.A.S | UNKNOWN |
| University Hospital, Strasbourg, France | OTHER |
| Hospices Civils de Lyon |
It is established that the surviving patients after a stay in the ICU are characterized by frequent malnutrition and morbidity and mortality. The main goal of this work is to study the relationship between nutritional statuses during ICU hospitalization, whatever its determinants, and quality of life, morbidity and mortality at one year.
The hypothesis of the study is that the presence of under nutrition is responsible for a 10% increase in crude mortality at one year (which would be respectively 30% for malnourished patients and 20% for non-malnourished patients).
This is a multicenter cohort study of a 30-month follow-up on patients after a stay in ICU.
Nutritional parameters and evaluation of the quality of life will be collected during hospitalization and output during a visit to the Clinical Research Associate at 6 months and one year. Survival will be also noted. These parameters will be studied in comparative patients malnourished and non-malnourished.
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| Measure | Description | Time Frame |
|---|---|---|
| all-cause mortality | at one year |
| Measure | Description | Time Frame |
|---|---|---|
| Anxiety and depression | at inclusion, M6 and M12 | |
| Post-traumatic stress | at inclusion, M6 and M12 | |
| Quality of life |
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Inclusion Criteria:
Patients of both sexes, age greater than or equal to 18 years
Hospitalized more than 72 hours in the ICU
Requiring at least one support organ failure:
Affiliated to a social security system
Having given free, informed written consent
Exclusion Criteria:
Patients with end-stage disease or for which a limitation of care was decided
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patients malnourished and non-malnourished
| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Patrick LACARIN | Contact | 04 73 75 11 95 | placarin@chu-clermontferrand.fr |
| Name | Affiliation | Role |
|---|---|---|
| Noël CANO | University Hospital, Clermont-Ferrand | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Chu de Clermont-Ferrand | Clermont-Ferrand | 63003 | France |
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| OTHER |
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| at M6 and M12 |
| Degree of activity (Karnofsky questionnaire) | At M6 and M12 |
| Weight | at inclusion, M6 and M12 |
| Body mass index | at inclusion, M6 and M12 |
| Albumin | at inclusion, M6 and M12 |
| Orosomucoid | at inclusion, M6 and M12 |
| Transthyretin (prealbumin) | at inclusion, M6 and M12 |
| Body composition | at inclusion, M6 and M12 |