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| Name | Class |
|---|---|
| Academy of Finland | OTHER |
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Single blind randomized clinical trial including 50 stroke patients to investigate the effect of daily music listening on behavioral, neural and physiological recovery. Patients are randomized (1:1:1) to listen instrumental or vocal music, or audiobooks (recorded book reading) (control). Outcome measures are change in neuropsychological tests, change in self-reported mood, structural and functional magnetic resonance imaging changes and hormonal changes performed at acute, 3-month and 6-month stages.
Please see above
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Instrumental music listening | Experimental | Daily music listening |
|
| Vocal music listening | Experimental | Daily music listening |
|
| Audiobook listening (control) | Active Comparator | Daily audiobook listening |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Music listening | Behavioral |
| ||
| Audiobook listening |
| Measure | Description | Time Frame |
|---|---|---|
| Change in neuropsychological performance (verbal memory) | Verbal memory summary score (Rivermead Behavioral Memory Test (RBMT) story recall, auditory-verbal learning task) | From acute to 3-month-stage |
| Change in neuropsychological performance (verbal memory) | Verbal memory summary score (RBMT story recall, auditory-verbal learning task) | From acute to 6-month-stage |
| Measure | Description | Time Frame |
|---|---|---|
| Change in neuropsychological performance (Language skill) | Verbal fluency task | From acute to 3-month-stage |
| Change in neuropsychological performance (Language skill) | Naming test CERAD/Boston Naming Test (BNT) |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Valtteri Kaasinen, MD | Department of Clinical Neurosciences | Study Chair |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Turku University Hospital | Turku | Finland |
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| ID | Term |
|---|---|
| D020521 | Stroke |
| ID | Term |
|---|---|
| D002561 | Cerebrovascular Disorders |
| D001927 | Brain Diseases |
| D002493 | Central Nervous System Diseases |
| D009422 | Nervous System Diseases |
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| Behavioral |
|
| From acute to 3-month-stage |
| Change in neuropsychological performance (Language skill) | Short Token Test | From acute to 3-month-stage |
| Change in neuropsychological performance (Language skill) | Verbal fluency task | From acute to 6-month-stages |
| Change in neuropsychological performance (Language skill) | Naming test CERAD/BNT | From acute to 6-month-stages |
| Change in neuropsychological performance (Language skill) | Short Token Test | From acute to 6-month-stages |
| Change in mood | Profile of Mood States | From acute to 3-month-stage |
| Change in mood | Profile of Mood States | From acute to 6-month-stage |
| Change in structural gray matter | Voxel-based morphometry | From acute to 3-month-stage |
| Change in structural gray matter changes | Voxel-based morphometry | From acute to 6-month-stage |
| Change in structural white matter | Diffusion-weighted imaging | From acute to 3-month stage |
| Change in structural white matter | Diffusion-weighted imaging | From acute to 6-month stage |
| Change in neuronal function | Resting state/task-based fMRI | From acute to 3-month stage |
| Change in neuronal function | Resting state/task-based fMRI | From acute to 6-month stage |
| Change in physiological stress level | Cortisol serum concentration | From acute to 3-month-stage |
| Change in physiological stress level | Cortisol serum concentration | From acute to 6-month-stage |
| Change in physiological stress level | Beta-endorphin serum concentration | From acute to 3-month-stage |
| Change in physiological stress level | Beta-endorphin serum concentration | From acute to 6-month-stage |
| Change in physiological stress level | Oxytocin serum concentration | From acute to 3-month-stage |
| Change in physiological stress level | Oxytocin serum concentration | From acute to 6-month-stage |
| D014652 | Vascular Diseases |
| D002318 | Cardiovascular Diseases |