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| Name | Class |
|---|---|
| Norwegian School of Sport Sciences | OTHER |
| University Hospital, Akershus | OTHER |
| Vestre Viken Hospital Trust | OTHER |
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The purpose of the study is to investigate the change in pulmonary function and exercise capacity in lung cancer patients after pulmonary resection. Furthermore, to study the effect of training on aerobic capacity, muscular strength, morbidity and survival. Physical activity level by accelerometers, body composition by DXA and quality of life will also be reported.
Five year after surgery, all included patients will be reinvited to undergo a fourth health excame to study the long-term effects of exercise training on physical fitness, morbidity and survival.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Physical training | Other | Exercise intervention. |
|
| As usual | Other | Controls |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Physical training | Other | Physical training three times a week for 20 week including endurance and strength training compare to the "as usual" group as controls |
|
| Measure | Description | Time Frame |
|---|---|---|
| Change in Maximal oxygen uptake (VO2max) from baseline | Change in VO2max from before to after surgery to measure the effect of surgery, and after six months to measure the effect of high-intensity training intervention, and after five years to study long-term effects | An expected average of two weeks before surgery (baseline), four to six weeks after surgery, after six months and after 5 years |
| Measure | Description | Time Frame |
|---|---|---|
| Change in Pulmonary function from baseline | Change in pulmonary function from before to after surgery and after the intervention | Pulmonary function is measured three times; an expected average of two weeks before surgery, four to six weeks after surgery, after after six months and after five years. |
| Measure | Description | Time Frame |
|---|---|---|
| DXA scan | Change in body composition from before to after surgery and after the intervention | An expected average of two weeks before surgery, four to six weeks after surgery, after six months and after five years |
| Quality of life |
Inclusion Criteria:
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Elisabeth Edvardsen, PhD | Oslo University Hospital | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Oslo University Hospital | Oslo | 0450 | Norway |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 25323620 | Background | Edvardsen E, Skjonsberg OH, Holme I, Nordsletten L, Borchsenius F, Anderssen SA. High-intensity training following lung cancer surgery: a randomised controlled trial. Thorax. 2015 Mar;70(3):244-50. doi: 10.1136/thoraxjnl-2014-205944. Epub 2014 Oct 16. | |
| 27900127 | Derived | Edvardsen E, Anderssen SA, Borchsenius F, Skjonsberg OH. Reduction in cardiorespiratory fitness after lung resection is not related to the number of lung segments removed. BMJ Open Sport Exerc Med. 2015 Oct 5;1(1):e000032. doi: 10.1136/bmjsem-2015-000032. eCollection 2015. |
| Label | URL |
|---|---|
| Reduction in cardiorespiratory fitness after lung resection is not related to the number of lung segments removed | View source |
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| ID | Term |
|---|---|
| D008175 | Lung Neoplasms |
| ID | Term |
|---|---|
| D012142 | Respiratory Tract Neoplasms |
| D013899 | Thoracic Neoplasms |
| D009371 | Neoplasms by Site |
| D009369 | Neoplasms |
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| ID | Term |
|---|---|
| D064797 | Physical Conditioning, Human |
| ID | Term |
|---|---|
| D015444 | Exercise |
| D009043 | Motor Activity |
| D009068 | Movement |
| D009142 | Musculoskeletal Physiological Phenomena |
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| As usual | Other | Controls, not training |
|
Change in quality of life from before to after surgery and after the intervention
| Measured three times: An expected average of two weeks before surgery, four to six weeks after surgery, after six months and after five years |
| Physical activity | Physical activity will be objectively measured by accelerometers for seven consecutive days to determine change in activity level after surgery | Measured three times: six weeks after surgery, after six months and after five years |
| D008171 |
| Lung Diseases |
| D012140 | Respiratory Tract Diseases |
| D055687 |
| Musculoskeletal and Neural Physiological Phenomena |