The aim of this study is to estimate the burden of disease due to pneumococci, other bacteria and viruses in the African meningitis belt prior to pneumococcal conjugate vaccine introduction and to estimate the population impact of the vaccine after its implementation in 2014. In a defined population of a sanitary district in northern Togo, during the period 2010 to 2017, investigators enroll patients of all ages with suspected pneumonia requiring hospitalization or suspected bacterial meningitis. Patients are evaluated by bacteriology and molecular biology techniques on blood, cerebro-spinal fluid, nasal aspirates and by chest X-ray.

Pneumonia surveillance:

Inclusion Criteria:

• resident of Tône sanitary district - requiring hospitalisation for at least one night for clinical pneumonia syndrome
• hospitalised in a study site during the study period

Exclusion Criteria:

• absence of informed consent by patient or legal tutor

Meningitis surveillance:

Inclusion Criteria:

• resident of Tône sanitary district
• presenting clinical signs of acute bacterial meningitis
• hospitalised in a study site during the study period

Exclusion Criteria:

• absence of informed consent by patient or legal tutor

Pneumonia surveillance:

-residents of Tône sanitary district requiring hospitaliation for suspected pneumonia and presenting at one of the hospitals of Dapaong town (district capital)

Meningitis surveillance:

- residents fo Tône sanitary district presenting with suspected meningitis at one of the hospitals of Dapaong town (district capital) or Sinkasse health center