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| Name | Class |
|---|---|
| Northern State Medical University | OTHER |
The aim of study is to determine effect of enhanced recovery after surgery (ERAS) on inflammatory response after abdominal hysterectomy.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Conventional therapy | |||
| ERAS | Oral intake of solid food restriction 6 hours before surgery. Oral intake clear fluids restriction 2 hours before surgery. Intravenous 5% Dextrose-500 ml 1 hour before surgery. Intravenous dexamethasone -4mg before anesthesia. Combined spinal-epidural anesthesia. Intraoperatively 10 ml/kg intravenous of crystalloids. Paracetamol intravenous 1g. Early mobilization of patient. Oral solid food intake 4 hour postoperative. Postoperative continuous epidural analgesia. |
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| Measure | Description | Time Frame |
|---|---|---|
| Change of Serum level of IL-1beta,IL-6,CRP,Cortisol,IL-4 by immuno-ferment analysis. | baseline, 24 hour post-operative and 7 days post-operative |
| Measure | Description | Time Frame |
|---|---|---|
| Change of postoperative pain, fatigue and postoperative nausea and vomiting | Postoperative pain will be assessed by visual analogue scale. Postoperative fatigue will be assessed by modified analogue scale. incidence of postoperative of nausea and vomiting | baseline,6,12,24,48 hour and 7 days postoperatively |
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Inclusion Criteria:
Exclusion Criteria:
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Admitted patients in maternity home
| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Eduard Ed. Antypin, MD | Contact | 0079600114083 | vard67@mail.ru | |
| Ayyaz Hussain, MD | Contact | 0079115848504 | ayyaz@mail.ru |
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Samoilova maternity home | Recruiting | Arkhangelsk | Arkhangelskya Oblast | 163000 | Russia |
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serum