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| Name | Class |
|---|---|
| Fundação de Amparo à Pesquisa do Estado de São Paulo | OTHER_GOV |
| Conselho Nacional de Desenvolvimento Científico e Tecnológico | OTHER_GOV |
| Coordenação de Aperfeiçoamento de Pessoal de Nível Superior. |
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The purpose of this study is to investigate anthropometric, metabolic, cardiovascular and symptomatic profiles in postmenopausal women.
When aging, the body composition changes, leading to a reduction of muscle mass and strength, and to an increase in total body fat. These body composition changes have especially been observed in postmenopausal women, due to the hormonal changes taking place. After the menopause, the gynoid fat distribution with fat deposits in the gluteo-femoral region changes to an android fat distribution with an increased upper body fat, especially in the abdominal region. These consequences of the menopause associated with a decrease in aerobic capacity and reduced total energy expenditure may lead to the metabolic syndrome (MetS). The aim of this study was to investigate the anthropometric, metabolic, cardiovascular and symptomatic profile in gynoid and android postmenopausal women.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| android postmenopausal women | Clinical exams |
| |
| gynoid postmenopausal women | Clinical exams |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Clinical exams | Other | Physiological and biochemical tests; quality of life questionnaire; body composition measurement |
|
| Measure | Description | Time Frame |
|---|---|---|
| Relationships between postmenopause and fat distribution | Anthropometric measurements: waist-to-hip ratio and body mass index | Baseline |
| Measure | Description | Time Frame |
|---|---|---|
| Comparison of aerobic capacity between android and gynoid postmenopausal women | Progressive aerobic testing on treadmill (Modified Bruce Protocol): estimated maximum oxygen consumption; metabolic equivalents; blood pressure; heart rate | Baseline |
| Comparison of metabolic parameters between android and gynoid postmenopausal women |
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Inclusion Criteria:
Exclusion Criteria:
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Postmenopausal women from a community sample of São Carlos city - São Paulo State - Brazil.
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| Name | Affiliation | Role |
|---|---|---|
| Audrey Borghi-Silva, Ph.D | Department of Physical Therapy, Federal University of São Carlos (UFSCar) | Study Director |
| Cristina Kurachi, Ph.D | Physics Institute of São Carlos (IFSC), University of São Paulo (USP) | Study Director |
| Vanderlei S Bagnato, Ph.D | Physics Institute of São Carlos (IFSC), University of São Paulo (USP) | Study Director |
| Fernanda R. Paolillo, Ph.D | Physics Institute of São Carlos (IFSC), University of São Paulo (USP) | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Optics Group from Physics Institute of São Carlos (IFSC), University of São Paulo (USP) | São Carlos | São Paulo | 676 | Brazil |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 22089183 | Background | Paolillo FR, Milan JC, Bueno Pde G, Paolillo AR, Borghi-Silva A, Parizotto NA, Arena R, Kurachi C, Bagnato VS. Effects of excess body mass on strength and fatigability of quadriceps in postmenopausal women. Menopause. 2012 May;19(5):556-61. doi: 10.1097/gme.0b013e3182364e80. | |
| 21749263 | Background | Paolillo FR, Milan JC, Aniceto IV, Barreto SG, Rebelatto JR, Borghi-Silva A, Parizotto NA, Kurachi C, Bagnato VS. Effects of infrared-LED illumination applied during high-intensity treadmill training in postmenopausal women. Photomed Laser Surg. 2011 Sep;29(9):639-45. doi: 10.1089/pho.2010.2961. Epub 2011 Jul 12. |
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| ID | Term |
|---|---|
| D024821 | Metabolic Syndrome |
| ID | Term |
|---|---|
| D007333 | Insulin Resistance |
| D006946 | Hyperinsulinism |
| D044882 | Glucose Metabolism Disorders |
| D008659 | Metabolic Diseases |
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Biochemical tests: the serum level of estradiol, urea, creatinine, triglycerides, total cholesterol, high-density lipoprotein (HDL) cholesterol, low-density lipoprotein (LDL) cholesterol, very low-density lipoprotein (VLDL) cholesterol, insulin and glucose |
| Baseline |
| Comparison of quality of life between android and gynoid postmenopausal women | Menopause Rating Scale (MRS): somatic symptoms; psychological symptoms; urogenital-sexual problems | Baseline |
| Comparison of the body composition between android and gynoid postmenopausal women | Body composition: bipolar electrical bioimpedance (body fat and lean mass) and skinfolds (triceps, subscapular, suprailiac, abdominal, anterior thigh, medial calf) | Baseline |
| 22382875 | Background | Paolillo FR, Corazza AV, Borghi-Silva A, Parizotto NA, Kurachi C, Bagnato VS. Infrared LED irradiation applied during high-intensity treadmill training improves maximal exercise tolerance in postmenopausal women: a 6-month longitudinal study. Lasers Med Sci. 2013 Feb;28(2):415-22. doi: 10.1007/s10103-012-1062-y. Epub 2012 Mar 2. |
| 22067278 | Background | Blumel JE, Legorreta D, Chedraui P, Ayala F, Bencosme A, Danckers L, Lange D, Espinoza MT, Gomez G, Grandia E, Izaguirre H, Manriquez V, Martino M, Navarro D, Ojeda E, Onatra W, Pozzo E, Prada M, Royer M, Saavedra JM, Sayegh F, Tserotas K, Vallejo MS, Zuniga C; Collaborative Group for Research of the Climacteric in Latin America (REDLINC). Optimal waist circumference cutoff value for defining the metabolic syndrome in postmenopausal Latin American women. Menopause. 2012 Apr;19(4):433-7. doi: 10.1097/gme.0b013e318231fc79. |
| 17167477 | Background | Despres JP, Lemieux I. Abdominal obesity and metabolic syndrome. Nature. 2006 Dec 14;444(7121):881-7. doi: 10.1038/nature05488. |
| D009750 |
| Nutritional and Metabolic Diseases |