Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
| Name | Class |
|---|---|
| National Aeronautics and Space Administration (NASA) | FED |
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
The purpose of this study is to validate the acceptability, operational feasibility and efficacy of a combined fatigue countermeasure comprised of shorter-wavelength light and exercise during operational Orbit 1 night shifts to improve alertness and performance of flight mission controllers.
Specifically, the investigators will:
Each participant will have three data collection periods. Each data collection period will last one shift rotation (5 -7 days): One 5-shift or 7-shift block of Orbit 1 night shifts on console with access to photic and exercise countermeasures, a second 5-shift or 7-shift block of Orbit 1 night shifts on console with no access to countermeasures, and a third 5-shift block of daytime office work off console. We will be measuring sleep via a wrist worn activity measuring device and compliance of exercise intervention via a small, commercially available heart monitor worn around the chest underneath clothing. The activity device will be worn continuously and the heart monitor will be worn on shift. These devices will be downloaded at the end of each block of shifts. Subjects will complete a short baseline questionnaire once at the beginning of the study. Subjective alertness will be assessed with the Karolinska Sleepiness Scale (KSS), performance testing will occur regularly and 'end of shift' questionnaires will be completed at the end of each shift. Drowsiness will be measured on the commute to and from work with the Optalert.
Not provided
Not provided
Not provided
Not provided
Not provided
| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Access to experimental break room | Experimental | Subjects will visit the experimental break room 4 times per Orbit 1 shift:
In the break room, subjects will be passively exposed to blue-wavelength enriched ceiling lights during all four visits for each work shift. Also in the break room, subjects will perform 10-minutes of mild exercise during the first three visits to the break room during each work shift. |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| blue-wavelength enriched ceiling light | Behavioral | Subjects will be in the experimental break room for four 20-minute periods for each Orbit 1 work shift. |
|
| Measure | Description | Time Frame |
|---|---|---|
| Alertness/Fatigue as measured by Psychomotor Vigilance Task and Visual Analog Scales | Average slowest 10% reaction times by condition (day shift, overnight control, overnight intervention), across time within shifts (pre-shift, first half, second half, post-shift), and across consecutive shifts (shifts 1, 2, 3, 4, 5) | Three weeks. |
| Measure | Description | Time Frame |
|---|---|---|
| Sleep duration as measured by wrist actigraphy | Average hours of sleep per 24hr day by condition (day shift, overnight control, overnight intervention) | Three weeks. |
| Sleep duration as captured in sleep/work logs |
Not provided
Inclusion Criteria:
Exclusion Criteria:
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
| Name | Affiliation | Role |
|---|---|---|
| Charles A Czeisler, PhD, MD | Brigham and Women's Hospital / Harvard Medical School | Principal Investigator |
| Laura K Barger, PhD | Brigham and Women's Hospital / Harvard Medical School | Study Director |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Johnson Space Center | Houston | Texas | 77058 | United States |
Not provided
| ID | Term |
|---|---|
| D005221 | Fatigue |
| ID | Term |
|---|---|
| D012816 | Signs and Symptoms |
| D013568 | Pathological Conditions, Signs and Symptoms |
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
|
| mild exercise | Behavioral | Subjects will be asked to achieve 65% of maximum heart rate on either a treadmill or exercise cycle for 10-minutes, three times during each Orbit 1 work shift. |
|
|
Average hours of sleep per 24hr day by condition (day shift, overnight control, overnight intervention)
| Three weeks. |