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We were not able to recruit enough patients for this study within a given time frame.
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The purpose of this study is to investigate, whether leech therapy for the treatment of postherpetic pain improves pain and sensory function.
Therefore 20 patients with PHN undergoing leech therapy at the investigators outpatient clinic will be included in this observational trial.
see above
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Leech therapy | Patients receiving leech therapy in the outpatient clinic |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Leech therapy | Procedure | Leech therapy: Using medicinal leeches After piercing the skin and injecting anticoagulants (hirudin) and anaesthetics, they suck out blood of the incision. After 30 to 60 minutes they fall off and the wound -after a short time of after-bleeding- is bandaged up. |
| Measure | Description | Time Frame |
|---|---|---|
| Pain intensity | Pain intensity measured on a visual analogue scale (0-100mm, 100mm indicating worst pain imaginable) | 28 days |
| Measure | Description | Time Frame |
|---|---|---|
| Pain intensity | pain intensity on a 100mm Visual Analogue Scale | 3 months |
| Pain quality | sensory and affective dimensions of pain (measured by the McGill Pain Questionnaire) |
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Inclusion Criteria:
Exclusion Criteria:
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patients from an outpatient clinic for naturopathy, traditional chinese and indian medicine(secondary care)
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| Name | Affiliation | Role |
|---|---|---|
| Romy Lauche, PhD | Research fellow | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Chair of Complementary and Integrative Medicine | Essen | 45276 | Germany |
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| ID | Term |
|---|---|
| D051474 | Neuralgia, Postherpetic |
| ID | Term |
|---|---|
| D009437 | Neuralgia |
| D010523 | Peripheral Nervous System Diseases |
| D009468 | Neuromuscular Diseases |
| D009422 | Nervous System Diseases |
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| ID | Term |
|---|---|
| D024763 | Leeching |
| ID | Term |
|---|---|
| D013812 | Therapeutics |
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|
|
| 28 Days |
| Pain quality | sensory and affective dimensions of pain (measured by the McGill Pain Questionnaire) | 3 months |
| Impairment | functional impairment due to zoster pain, measured bey the zoster brief pain inventory and the zoster impact questionnaire (Coplan P, Schmader K, Nikas A, Chan I, Choo P, Levin M, Johnson G, Bauer M, Williams HM, Kapla KM, Guess HA, Oxman MN. (2004). Development of a measure of the burden of pain due to herpes zoster and postherpetic neuralgia for prevention trials: adaptation of the brief pain inventory. J Pain, 5(6), 344-356.) | 28 days |
| Impairment | functional impairment due to zoster pain, measured bey the zoster brief pain inventory and the zoster impact questionnaire (Coplan P, Schmader K, Nikas A, Chan I, Choo P, Levin M, Johnson G, Bauer M, Williams HM, Kapla KM, Guess HA, Oxman MN. (2004). Development of a measure of the burden of pain due to herpes zoster and postherpetic neuralgia for prevention trials: adaptation of the brief pain inventory. J Pain, 5(6), 344-356.) | 3 months |
| Quality of life | quality of life measured by the SF36 | 28 days |
| quality of life | quality of life measured by the SF36 | 3 months |
| Sensory perception and pain thresholds | Sensory perception and pain thresholds measured by the quantitative sensory testing battery (Rolke, R., Magerl, W., Campbell, K. A., Schalber, C., Caspari, S., Birklein, F. and Treede, R.-D. (2006), Quantitative sensory testing: a comprehensive protocol for clinical trials. European Journal of Pain, 10: 77.) | 28 days |
| Sensory perception and pain thresholds | Sensory perception and pain thresholds measured by the quantitative sensory testing battery (Rolke, R., Magerl, W., Campbell, K. A., Schalber, C., Caspari, S., Birklein, F. and Treede, R.-D. (2006), Quantitative sensory testing: a comprehensive protocol for clinical trials. European Journal of Pain, 10: 77.) | 3 months |
| Safety | all adverse and serious adverse events | 28 days |
| D010146 | Pain |
| D009461 | Neurologic Manifestations |
| D012816 | Signs and Symptoms |
| D013568 | Pathological Conditions, Signs and Symptoms |